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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	135450-94-1
Molecular formula	C12H14N6OS
IUPAC name	N-[[6-[2-(diaminomethylideneamino)-1,3-thiazol-4-yl]pyridin-2-yl]methyl]acetamide
Molecular weight	290.345
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	-0.5
Synonyms	AOCMLOWDFAEKJE-UHFFFAOYSA-N N-[[6-[2-[(Diaminomethylene)amino]-4-thiazolyl]-2-pyridinyl]methyl]acetamide 4-(6-acetylaminomethylpyridin-2-yl)-2-(diaminomethyleneamino)thiazole CHEMBL556048 Acetamide, N-((6-(2-((aminoiminomethyl)amino)-4-thiazolyl)-2-pyridinyl)methyl)- N-((6-(2-((Aminoiminomethyl)amino)-4-thiazolyl)-2-pyridinyl)methyl)acetamide 4-(6-(ACETAMIDOMETHYL)(PYRIDIN-2-YL))-2-GUANIDINOTHIAZOLE BDBM50036755 SCHEMBL9296782 4-Apgt CTK4B9825 AKOS030547480 N-[6-(2-Guanidino-thiazol-4-yl)-pyridin-2-ylmethyl]-acetamide; hydrochloride 4-(6-(Acetamidomethyl)pyridin-2-yl)-2-guanidinothiazole CHEMBL1196182 L004994 [ Show all ]
Inchi Key	AOCMLOWDFAEKJE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C12H14N6OS/c1-7(19)15-5-8-3-2-4-9(16-8)10-6-20-12(17-10)18-11(13)14/h2-4,6H,5H2,1H3,(H,15,19)(H4,13,14,17,18)
PubChem CID	10446940
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50036755
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
10119	Histamine H2 receptor	P47747	HRH2	Cavia porcellus (Guinea pig)	359

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