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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL103636
Molecular formula	C22H23F3N4O
IUPAC name	2-(2-methylpyridin-3-yl)-2-[4-(4,4,4-trifluoro-3-phenylbutanoyl)piperazin-1-yl]acetonitrile
Molecular weight	416.448
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	3.1
Synonyms	BDBM50046017 SCHEMBL9575115 (2-Methyl-pyridin-3-yl)-[4-(4,4,4-trifluoro-3-phenyl-butyryl)-piperazin-1-yl]-acetonitrile
Inchi Key	DJVGGWBBBINHRQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H23F3N4O/c1-16-18(8-5-9-27-16)20(15-26)28-10-12-29(13-11-28)21(30)14-19(22(23,24)25)17-6-3-2-4-7-17/h2-9,19-20H,10-14H2,1H3
PubChem CID	10364589
ChEMBL	CHEMBL103636
IUPHAR	N/A
BindingDB	50046017
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
61850	Platelet-activating factor receptor	Q62035	Ptafr	Mus musculus (Mouse)	341
61851	Platelet-activating factor receptor	P46002	Ptafr	Rattus norvegicus (Rat)	341
61852	Platelet-activating factor receptor	P21556	PTAFR	Cavia porcellus (Guinea pig)	342

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