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Ligand

NameCHEMBL184983
Molecular formulaC17H18Cl2FNO5
IUPAC name(1R,2R,3R,5R,6R)-2-amino-3-[(1R)-1-(3,4-dichlorophenyl)propoxy]-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Molecular weight406.231
Hydrogen bond acceptor7
Hydrogen bond donor3
XlogP0.3
SynonymsBDBM50151481
(1R,2R,3R,5R,6R)-2-Amino-3-[(R)-1-(3,4-dichloro-phenyl)-propoxy]-6-fluoro-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Inchi KeyDQUWONNIKAVHTA-UVUDQEGWSA-N
Inchi IDInChI=1S/C17H18Cl2FNO5/c1-2-11(7-3-4-9(18)10(19)5-7)26-12-6-8-13(16(8,20)14(22)23)17(12,21)15(24)25/h3-5,8,11-13H,2,6,21H2,1H3,(H,22,23)(H,24,25)/t8-,11-,12-,13+,16-,17+/m1/s1
PubChem CID11177216
ChEMBLCHEMBL184983
IUPHARN/A
BindingDB50151481
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 2
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
66649Metabotropic glutamate receptor 2P31421Grm2Rattus norvegicus (Rat)872
559367Metabotropic glutamate receptor 2Q14416GRM2Homo sapiens (Human)872

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