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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3288680
Molecular formula	C26H18N4O
IUPAC name	8-isoquinolin-7-yl-4-methyl-2-phenylpyrazolo[1,5-a]quinazolin-5-one
Molecular weight	402.457
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	4.8
Synonyms	BDBM50017665
Inchi Key	DUOKBXVNMNQTRT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H18N4O/c1-29-25-15-23(18-5-3-2-4-6-18)28-30(25)24-14-20(9-10-22(24)26(29)31)19-8-7-17-11-12-27-16-21(17)13-19/h2-16H,1H3
PubChem CID	90643976
ChEMBL	CHEMBL3288680
IUPHAR	N/A
BindingDB	50017665
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
69278	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
559470	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
69277	Metabotropic glutamate receptor 3	P31422	Grm3	Rattus norvegicus (Rat)	879

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