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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	S-16924
Molecular formula	C22H24FNO4
IUPAC name	2-[1-[2-(2,3-dihydro-1,4-benzodioxin-5-yloxy)ethyl]pyrrolidin-3-yl]-1-(4-fluorophenyl)ethanone
Molecular weight	385.435
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	3.4
Synonyms	169167-86-6 GTPL167 s16924 2-[1-[2-(2,3-dihydro-1,4-benzodioxin-8-yloxy)ethyl]pyrrolidin-3-yl]-1-(4-fluorophenyl)ethanone S 16924 SCHEMBL8109895 D0T6BA [ Show all ]
Inchi Key	DXBFVLGYPFUTEZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H24FNO4/c23-18-6-4-17(5-7-18)19(25)14-16-8-9-24(15-16)10-11-26-20-2-1-3-21-22(20)28-13-12-27-21/h1-7,16H,8-15H2
PubChem CID	9821498
ChEMBL	N/A
IUPHAR	167
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
553619	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
553622	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
553621	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
553623	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
553620	5-hydroxytryptamine receptor 6	P31388	Htr6	Rattus norvegicus (Rat)	436

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