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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1093125
Molecular formula	C28H19F3N2O5S
IUPAC name	(E)-3-[3-hydroxy-1-(naphthalen-2-ylmethyl)-2-oxo-3H-indol-7-yl]-N-(2,4,5-trifluorophenyl)sulfonylprop-2-enamide
Molecular weight	552.524
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	4.3
Synonyms	3-(3-hydroxy-1-(naphthalen-2-ylmethyl)-2-oxoindolin-7-yl)-N-(2,4,5-trifluorophenylsulfonyl)acrylamide BDBM50315469
Inchi Key	FBMLUXABXAEURE-ZHACJKMWSA-N
Inchi ID	InChI=1S/C28H19F3N2O5S/c29-21-13-23(31)24(14-22(21)30)39(37,38)32-25(34)11-10-18-6-3-7-20-26(18)33(28(36)27(20)35)15-16-8-9-17-4-1-2-5-19(17)12-16/h1-14,27,35H,15H2,(H,32,34)/b11-10+
PubChem CID	46885735
ChEMBL	CHEMBL1093125
IUPHAR	N/A
BindingDB	50315469
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
74335	Prostacyclin receptor	P43119	PTGIR	Homo sapiens (Human)	386
74336	Prostaglandin E2 receptor EP2 subtype	P43116	PTGER2	Homo sapiens (Human)	358
74337	Prostaglandin E2 receptor EP3 subtype	P43115	PTGER3	Homo sapiens (Human)	390
74334	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488
74338	Prostaglandin F2-alpha receptor	P43088	PTGFR	Homo sapiens (Human)	359

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