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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL256492
Molecular formula	C21H27FN2O3
IUPAC name	1-[[4-(2-fluoroethoxy)-3-methoxyphenyl]methyl]-4-(2-methoxyphenyl)piperazine
Molecular weight	374.456
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	3.6
Synonyms	BDBM50373708
Inchi Key	FKHJOYFNYFVDRF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H27FN2O3/c1-25-19-6-4-3-5-18(19)24-12-10-23(11-13-24)16-17-7-8-20(27-14-9-22)21(15-17)26-2/h3-8,15H,9-14,16H2,1-2H3
PubChem CID	44454735
ChEMBL	CHEMBL256492
IUPHAR	N/A
BindingDB	50373708
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
80457	5-hydroxytryptamine receptor 2A	P50129	HTR2A	Sus scrofa (Pig)	470
80456	D(1A) dopamine receptor	P50130	DRD1	Sus scrofa (Pig)	446
80458	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
80459	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
523870	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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