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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL173811
Molecular formula	C19H31NO5S2
IUPAC name	7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[3-hydroxy-4-(1,3-thiazol-2-ylsulfanyl)butyl]cyclopentyl]heptanoic acid
Molecular weight	417.579
Hydrogen bond acceptor	8
Hydrogen bond donor	4
XlogP	3.1
Synonyms	BDBM50085915 7-{3,5-Dihydroxy-2-[3-hydroxy-4-(thiazol-2-ylsulfanyl)-butyl]-cyclopentyl}-heptanoic acid 9alpha,11alpha,15-Trihydroxy-17-(thiazole-2-yl)-18,19,20-trinor-17-thiaprostane-1-oic acid
Inchi Key	FNZKSJLLEXLFRT-MUOSFQKXSA-N
Inchi ID	InChI=1S/C19H31NO5S2/c21-13(12-27-19-20-9-10-26-19)7-8-15-14(16(22)11-17(15)23)5-3-1-2-4-6-18(24)25/h9-10,13-17,21-23H,1-8,11-12H2,(H,24,25)/t13?,14-,15-,16+,17-/m1/s1
PubChem CID	10740699
ChEMBL	CHEMBL173811
IUPHAR	N/A
BindingDB	50085915
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
83062	Prostacyclin receptor	P43119	PTGIR	Homo sapiens (Human)	386
83057	Prostaglandin D2 receptor	Q13258	PTGDR	Homo sapiens (Human)	359
83063	Prostaglandin E2 receptor EP1 subtype	P34995	PTGER1	Homo sapiens (Human)	402
83059	Prostaglandin E2 receptor EP2 subtype	P43116	PTGER2	Homo sapiens (Human)	358
83058	Prostaglandin E2 receptor EP3 subtype	P43115	PTGER3	Homo sapiens (Human)	390
83060	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488
83061	Prostaglandin F2-alpha receptor	P43088	PTGFR	Homo sapiens (Human)	359
83056	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343

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