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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	UNII-C918IS60W6
Molecular formula	C11H16BrNO2
IUPAC name	(2R)-1-(4-bromo-2,5-dimethoxyphenyl)propan-2-amine
Molecular weight	274.158
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	2.6
Synonyms	Benzeneethanamine, 4-bromo-2,5-dimethoxy-alpha-methyl-, (alphaR)- R-(-)-2,5-Dimethoxy-4-bromoamphetamine (-)-2,5-Dimethoxy-4-bromoamphetamine C918IS60W6 ZINC92 (R)-1-(4-bromo-2,5-dimethoxyphenyl)propan-2-amine DTXSID70109993 Benzeneethanamine, 4-bromo-2,5-dimethoxy-alpha-methyl-, (R)- SCHEMBL1048339 (-)-Dob (R)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine BDBM50064708 PDSP2_001350 Brolamfetamine, (R)- (?)-DOB CHEMBL69700 43061-15-0 [ Show all ]
Inchi Key	FXMWUTGUCAKGQL-SSDOTTSWSA-N
Inchi ID	InChI=1S/C11H16BrNO2/c1-7(13)4-8-5-11(15-3)9(12)6-10(8)14-2/h5-7H,4,13H2,1-3H3/t7-/m1/s1
PubChem CID	12626561
ChEMBL	CHEMBL69700
IUPHAR	N/A
BindingDB	50064708
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
89731	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
89734	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
89736	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
89733	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
89732	Trace amine-associated receptor 1	Q8HZ64	TAAR1	Macaca mulatta (Rhesus macaque)	338
89735	Trace amine-associated receptor 1	Q96RJ0	TAAR1	Homo sapiens (Human)	339

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