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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL503605
Molecular formula	C13H14ClN3O
IUPAC name	(5-chloro-1H-indol-2-yl)-piperazin-1-ylmethanone
Molecular weight	263.725
Hydrogen bond acceptor	2
Hydrogen bond donor	2
XlogP	1.8
Synonyms	RNGVSSIIHLHHSN-UHFFFAOYSA-N BB 0247847 (5-Chloro-1H-indol-2-yl)-piperazin-1-yl-metha none SCHEMBL6130879 5-chloro-2-(piperazin-1-ylcarbonyl)-1H-indole BDBM26391 (5-Chloro-1H-indol-2-yl)-piperazin-1-yl-methanone JNJ 7777120 analogue, 4 ZINC32500347 AKOS016342960 (5-chloro-1H-indol-2-yl)(piperazino)methanone [ Show all ]
Inchi Key	RNGVSSIIHLHHSN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C13H14ClN3O/c14-10-1-2-11-9(7-10)8-12(16-11)13(18)17-5-3-15-4-6-17/h1-2,7-8,15-16H,3-6H2
PubChem CID	21638785
ChEMBL	CHEMBL503605
IUPHAR	N/A
BindingDB	26391
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
300481	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390
300482	Histamine H4 receptor	Q91ZY1	Hrh4	Rattus norvegicus (Rat)	391
300483	Histamine H4 receptor	Q91ZY2	Hrh4	Mus musculus (Mouse)	391

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