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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1081680
Molecular formula	C16H25N5
IUPAC name	4-[(3R)-3-aminopyrrolidin-1-yl]spiro[6,7-dihydro-5H-quinazoline-8,1'-cyclopentane]-2-amine
Molecular weight	287.411
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	2.2
Synonyms	BDBM50415771 SCHEMBL603650
Inchi Key	VYKIJFGQXTUGSK-LLVKDONJSA-N
Inchi ID	InChI=1S/C16H25N5/c17-11-5-9-21(10-11)14-12-4-3-8-16(6-1-2-7-16)13(12)19-15(18)20-14/h11H,1-10,17H2,(H2,18,19,20)/t11-/m1/s1
PubChem CID	44231733
ChEMBL	CHEMBL1081680
IUPHAR	N/A
BindingDB	50415771
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
367307	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445
367308	Histamine H3 receptor	Q9QYN8	Hrh3	Rattus norvegicus (Rat)	445
367309	Histamine H4 receptor	Q91ZY1	Hrh4	Rattus norvegicus (Rat)	391
367310	Histamine H4 receptor	Q91ZY2	Hrh4	Mus musculus (Mouse)	391
367311	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390

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