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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	2-Chloro-N6-cyclopentyladenosine
Molecular formula	C15H20ClN5O4
IUPAC name	(2R,3R,4S,5R)-2-[2-chloro-6-(cyclopentylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Molecular weight	369.806
Hydrogen bond acceptor	8
Hydrogen bond donor	4
XlogP	1.8
Synonyms	[3H]CCPA (2R,3R,4S,5R)-2-(2-Chloro-6-cyclopentylamino-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol 4824AB B6839 KB-23064 PDSP1_001070 2-(2-Chloro-6-cyclopentylamino-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol 2-Chloro-N6-cyclopentyladenosine, adenosine receptor agonist Adenosine, 2-chloro-N-cyclopentyl- C-21110 D0R1XY MolPort-003-940-643 PDSP2_001054 (2R,3R,4S,5R)-2-(2-chloro-6-(cyclopentylamino)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol 2-CHLORO-N-CYCLOPENTYLADENOSINE 37739-05-2 AN-17019 CCPA GTPL374 PDSP1_000305 ZINC3995998 (2R,3R,4S,5R)-2-[2-chloro-6-(cyclopentylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol 2-chloro-N6-cyclopentyladenosine (2-Cl-CPA) BDBM50085658 CHEMBL284969 LS-15108 PDSP2_000303 2-(2-Chloro-6-cyclopentylamino-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol(CCPA) 2-Cl-CPA AJ-47613 C15H20ClN5O4 DB-049183 N6-Cyclopentyl-2-chloroAdo SCHEMBL120439 [3H]-CCPA (2R,3R,4S,5R)-2-(2-chloro-6-(cyclopentylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol 2-chloro-n6-cyclopentyl-adenosine AX8016054 ccpa (biochemistry) GTPL379 PDSP1_000831 (2R,3R,4S,5R)-2-[2-chloro-6-(cyclopentylamino)purin-9-yl]-5-(hydroxymethyl)tetrahydrofuran-3,4-diol 2-Chloro-N6-cyclopentyladenosine hemihydrate AC1L3XBY BRN 4888162 D01LWZ MFCD00078574 PDSP2_000818 2-chloro-N(6)cyclopentyladenosine AKOS016009595 CC-10269 FT-0639402 NCGC00025266-02 XSMYYYQVWPZWIZ-IDTAVKCVSA-N [ Show all ]
Inchi Key	XSMYYYQVWPZWIZ-IDTAVKCVSA-N
Inchi ID	InChI=1S/C15H20ClN5O4/c16-15-19-12(18-7-3-1-2-4-7)9-13(20-15)21(6-17-9)14-11(24)10(23)8(5-22)25-14/h6-8,10-11,14,22-24H,1-5H2,(H,18,19,20)/t8-,10-,11-,14-/m1/s1
PubChem CID	123807
ChEMBL	CHEMBL284969
IUPHAR	379, 374
BindingDB	50085658
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
399813	Adenosine receptor A1	P28190	ADORA1	Bos taurus (Bovine)	326
399816	Adenosine receptor A1	P25099	Adora1	Rattus norvegicus (Rat)	326
399818	Adenosine receptor A1	P30542	ADORA1	Homo sapiens (Human)	326
399819	Adenosine receptor A1	Q60612	Adora1	Mus musculus (Mouse)	326
399820	Adenosine receptor A1	P47745	ADORA1	Cavia porcellus (Guinea pig)	326
399815	Adenosine receptor A2a	P29274	ADORA2A	Homo sapiens (Human)	412
399817	Adenosine receptor A2a	P30543	Adora2a	Rattus norvegicus (Rat)	410
399821	Adenosine receptor A2b	P29275	ADORA2B	Homo sapiens (Human)	332
399814	Adenosine receptor A3	P0DMS8	ADORA3	Homo sapiens (Human)	318
399822	Adenosine receptor A3	P28647	Adora3	Rattus norvegicus (Rat)	320

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