| Swiss ID: 5ht1a_human |
| Protein Name: 5-hydroxytryptamine 1A receptor (5-HT-1A) |
| Organism: Human |
| Seqeunce Length: 422 |
| MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAA IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED RSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADT RHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGN SKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLP FFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC RQ |
| Multiple Sequence Alignment |
| Experimental Restraints: |
| Contact Restraint: D82-D116 PMID of associated paper: 1426261 |
| Contact Restraint: D82-S391 PMID of associated paper: 8474430 |
| : MSA PMID of associated paper: 0 |
| Orientation Restraint: A50 PMID of associated paper: 15037200 |
| Orientation Restraint: L381 PMID of associated paper: 15037200 |
| Orientation Restraint: D82 PMID of associated paper: 1426261 |
| Orientation Restraint: D116 PMID of associated paper: 1426261 |
| Orientation Restraint: T200 PMID of associated paper: 1426261 |
| Orientation Restraint: S391 PMID of associated paper: 8474430 |
| Orientation Restraint: N396 PMID of associated paper: 8474430 |
| Experimental Data: |
| Experimental Data: P16L PMID of associated paper: 15037200 |
| Experimental Data: A17P PMID of associated paper: 15037200 |
| Experimental Data: G22S PMID of associated paper: 15037200 |
| Experimental Data: I28V PMID of associated paper: 15037200 |
| Experimental Data: A50V PMID of associated paper: 15037200 |
| Experimental Data: C109R PMID of associated paper: 15037200 |
| Experimental Data: P184L PMID of associated paper: 15037200 |
| Experimental Data: R220L PMID of associated paper: 15037200 |
| Experimental Data: K228R PMID of associated paper: 15037200 |
| Experimental Data: G273D PMID of associated paper: 15037200 |
| Experimental Data: L381F PMID of associated paper: 15037200 |
| Experimental Data: K418N PMID of associated paper: 15037200 |
| Experimental Data: D82N PMID of associated paper: 1426261 |
| Experimental Data: D116N PMID of associated paper: 1426261 |
| Experimental Data: T200A PMID of associated paper: 1426261 |
| Experimental Data: D82A PMID of associated paper: 8474430 |
| Experimental Data: S391A PMID of associated paper: 8474430 |
| Experimental Data: N396V PMID of associated paper: 8474430 |
| Experimental Data: N396Q PMID of associated paper: 8474430 |
| Experimental Data: N396A PMID of associated paper: 8474430 |
| Experimental Data: N396F PMID of associated paper: 8474430 |
| Experimental Data: D82-D116 PMID of associated paper: 1426261 |
| Experimental Data: D82-S391 PMID of associated paper: 8474430 |
| Experimental Data: A50V PMID of associated paper: 15037200 |
| Experimental Data: A155G PMID of associated paper: 15037200 |
| Experimental Data: M172I PMID of associated paper: 15037200 |
| Experimental Data: L381F PMID of associated paper: 15037200 |
| Experimental Data: D82N PMID of associated paper: 1426261 |
| Experimental Data: D116N PMID of associated paper: 1426261 |
| Experimental Data: S199A PMID of associated paper: 1426261 |
| Experimental Data: T200A PMID of associated paper: 1426261 |
| Experimental Data: D82A PMID of associated paper: 8474430 |
| Experimental Data: S391A PMID of associated paper: 8474430 |
| Experimental Data: S393A PMID of associated paper: 8474430 |
| Experimental Data: N396V PMID of associated paper: 8474430 |
| Experimental Data: N396Q PMID of associated paper: 8474430 |
| Experimental Data: N396A PMID of associated paper: 8474430 |
| Experimental Data: N396F PMID of associated paper: 8474430 |
| Experimental Data: N386V PMID of associated paper: 1349154 |
| Experimental Data: MSA PMID of associated paper: 0 |
| GPCR Related Corss-reference Links: |
| GPCRDB GPCR-OKB UniProt_P08908 |