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I-TASSER QUARK LOMETS COACH COFACTOR MUSTER SEGMER FG-MD ModRefiner REMO SPRING COTH BSpred SVMSEQ ANGLOR BSP-SLIM SAXSTER ThreaDom EvoDesign GPCR-I-TASSER

TM-score TM-align MMalign NWalign EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW CASP7 CASP8 CASP9 CASP10 CASP11


(The server completed predictions for 224118 proteins submitted by 56128 users from 117 countries)
(The template library was updated on 2015/04/16)

I-TASSER (Iterative Threading ASSEmbly Refinement) is a hierarchical method for protein structure and function prediction. Structural templates are first identified from the PDB by multiple threading approach LOMETS; full-length atomic models are constructed by iterative template fragment assembly simulations; function inslights of the target are finally derived by threading the 3D models through protein function database BioLiP. I-TASSER (as 'Zhang-Server') was ranked as the No 1 server for protein structure prediction in recent CASP7, CASP8, CASP9, CASP10, and CASP11 experiments. It was also ranked as the best for function prediction in CASP9. The server is in active development with the goal to provide the most accurate structural and function predictions using state-of-the-art algorithms. Please report problems and questions at I-TASSER message board and some members will study and answer the questions asap. (>> More about the server ...)

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I-TASSER On-line Server (View an example of I-TASSER output):
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