This page includes all the template library files needed for the I-TASSER, MUSTER, SEGMER, and LOMETS programs. All libraries are weekly updated.

• PDB (~715MB): PDB structures of a representative set of proteion templates (for I-TASSER, LOMETS, MUSTER and SEGMER).
• MTX (~255MB): Sequence profiles from PSI-BLAST search (for I-TASSER, LOMETS, MUSTER and SEGMER).
• DEP (~154MB): Structure profiles of templates (for I-TASSER, LOMETS, MUSTER and SEGMER).
• SIG (~165MB): Residue environmental profiles of templates (for I-TASSER, LOMETS).
• CNT (~64MB): Side-chain center contacts of templates (for I-TASSER, LOMETS).
• summary1 (~33MB): Sequence, secondary structure, solvent accessibilty, phi/psi angles (for I-TASSER, LOMETS, MUSTER and SEGMER).
• summary2 (~185MB): Training data for phi/psi prediction and contact prediction by SVM (for I-TASSER, LOMETS, MUSTER and SEGMER).

• I-TASSER:
  • A. Roy, A. Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, vol 5, 725-738 (2010). (download the PDF file).
  • Y. Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, vol 9, 40 (2008). (download the PDF file).
• LOMETS:
  • S Wu, Y Zhang. LOMETS: A local meta-threading-server for protein structure prediction. Nucleic Acids Research, 35: 3375-3382 (2007) (download the PDF file).
• MUSTER:
  • S. Wu, Y. Zhang. MUSTER: Improving protein sequence profile-profile alignments by using multiple sources of structure information. Proteins: Structure, Function, and Bioinformatics 2008; 72: 547-556. (download the PDF file)
• SEGMER:
  • S. Wu, Y. Zhang. SEGMER:identifying protein sub-structural similarity by segmental threading. Structure, 2010 18: 858-867 (download the PDF file).

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