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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Lysophosphatidic acid receptor 2
Species	Homo sapiens (Human)
Gene	LPAR2
Synonym	endothelial differentiation gene 4, lysophosphatidic acid G-protein-coupled receptor 4 LPA receptor 2 LPA-2 Edg4 Lysophosphatidic acid receptor Edg-4 Pbx4 pre-B-cell leukemia transcription factor 4 LPA2 receptor [ Show all ]
Disease	N/A
Length	351
Amino acid sequence	MVIMGQCYYNETIGFFYNNSGKELSSHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVMAVQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRTFRRLLCCACLRQSTRESVHYTSSAQGGASTRIMLPENGHPLMDSTL
UniProt	Q9HBW0
Protein Data Bank	N/A
GPCR-HGmod model	Q9HBW0
3D structure model	This predicted structure model is from GPCR-EXP Q9HBW0.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3724
IUPHAR	273
DrugBank	N/A

Ligand

Name	CHEMBL261872
Molecular formula	C17H14N2O4
IUPAC name	(Z)-4-(3-benzamidoanilino)-4-oxobut-2-enoic acid
Molecular weight	310.309
Hydrogen bond acceptor	4
Hydrogen bond donor	3
XlogP	1.6
Synonyms	4-{[3-(benzoylamino)phenyl]amino}-4-oxo-2-butenoic acid MLS000689930 AC1M330G SMR000298641 (Z)-4-(3-benzamidoanilino)-4-oxobut-2-enoic acid MolPort-002-213-708 BDBM50241460 SR-01000239753 HMS2628O20 4-(3-benzamidophenylamino)-4-oxobut-2-enoic acid AB00113230-01 SCHEMBL19174293 SR-01000239753-1 [ Show all ]
Inchi Key	OASSLTKLNUAPCY-KTKRTIGZSA-N
Inchi ID	InChI=1S/C17H14N2O4/c20-15(9-10-16(21)22)18-13-7-4-8-14(11-13)19-17(23)12-5-2-1-3-6-12/h1-11H,(H,18,20)(H,19,23)(H,21,22)/b10-9-
PubChem CID	2230607
ChEMBL	CHEMBL261872
IUPHAR	N/A
BindingDB	50241460
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Imax	46.0 %	PMID18467108	ChEMBL

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