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GPCR

NameP2Y purinoceptor 13
SpeciesHomo sapiens (Human)
GeneP2RY13
SynonymP2Y13
G-protein coupled receptor 86
purinergic receptor P2Y, G-protein coupled 13
G-protein coupled receptor 94
GPR94
[ Show all ]
DiseaseN/A
Length354
Amino acid sequenceMTAAIRRQRELSILPKVTLEAMNTTVMQGFNRSERCPRDTRIVQLVFPALYTVVFLTGILLNTLALWVFVHIPSSSTFIIYLKNTLVADLIMTLMLPFKILSDSHLAPWQLRAFVCRFSSVIFYETMYVGIVLLGLIAFDRFLKIIRPLRNIFLKKPVFAKTVSIFIWFFLFFISLPNTILSNKEATPSSVKKCASLKGPLGLKWHQMVNNICQFIFWTVFILMLVFYVVIAKKVYDSYRKSKSKDRKNNKKLEGKVFVVVAVFFVCFAPFHFARVPYTHSQTNNKTDCRLQNQLFIAKETTLFLAATNICMDPLIYIFLCKKFTEKLPCMQGRKTTASSQENHSSQTDNITLG
UniProtQ9BPV8
Protein Data BankN/A
GPCR-HGmod modelQ9BPV8
3D structure modelThis predicted structure model is from GPCR-EXP Q9BPV8.
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLN/A
IUPHAR329
DrugBankN/A

Ligand

NamePoly(2'-methylthioadenylic acid)
Molecular formulaC11H16N5O7PS
IUPAC name[(2R,3S,4R,5R)-5-(6-amino-2-methylsulfanylpurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
Molecular weight393.311
Hydrogen bond acceptor12
Hydrogen bond donor5
XlogP-2.7
Synonyms((2R,3S,4R,5R)-5-(6-Amino-2-(methylthio)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate
2-(methylsulfanyl)adenosine 5'-(dihydrogen phosphate)
2-(Methylthio)adenosine 5'-phosphoric acid
2-MeS-5'-AMP
2-MeSAMP
[ Show all ]
Inchi KeyXVTFTCNRRAQHEQ-KQYNXXCUSA-N
Inchi IDInChI=1S/C11H16N5O7PS/c1-25-11-14-8(12)5-9(15-11)16(3-13-5)10-7(18)6(17)4(23-10)2-22-24(19,20)21/h3-4,6-7,10,17-18H,2H2,1H3,(H2,12,14,15)(H2,19,20,21)/t4-,6-,7-,10-/m1/s1
PubChem CID189762
ChEMBLCHEMBL606240
IUPHAR1764
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand has more than 10 hydrogen bond acceptor.

Experimental Data

ParameterValueReferenceDatabase source
IC502511.89 nMPMID12815166IUPHAR

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