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GPCR

NameP2Y purinoceptor 1
SpeciesMeleagris gallopavo (Wild turkey)
GeneP2RY1
Synonym6H1 orphan receptor
ADP receptor
P2Y1
Purinergic receptor
DiseaseN/A for non-human GPCRs
Length362
Amino acid sequenceMTEALISAALNGTQPELLAGGWAAGNASTKCSLTKTGFQFYYLPTVYILVFITGFLGNSVAIWMFVFHMRPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDVMCKLQRFIFHVNLYGSILFLTCISVHRYTGVVHPLKSLGRLKKKNAVYVSSLVWALVVAVIAPILFYSGTGVRRNKTITCYDTTADEYLRSYFVYSMCTTVFMFCIPFIVILGCYGLIVKALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYLPFHVMKTLNLRARLDFQTPQMCAFNDKVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKSSRRSEPNVQSKSEEMTLNILTEYKQNGDTSL
UniProtP49652
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL5720
IUPHARN/A
DrugBankN/A

Ligand

NameCHEMBL331238
Molecular formulaC14H16ClN3O12P2S
IUPAC name4-chloro-3-[[5-hydroxy-6-methyl-3,4-bis(phosphonooxymethyl)pyridin-2-yl]diazenyl]benzenesulfonic acid
Molecular weight547.749
Hydrogen bond acceptor15
Hydrogen bond donor6
XlogP-1.6
Synonyms4-Chloro-3-(5-hydroxy-6-methyl-3,4-bis-phosphonooxymethyl-pyridin-2-ylazo)-benzenesulfonic acid
4-Chloro-3-[3,4-bis(phosphonooxymethyl)-5-hydroxy-6-methyl-2-pyridylazo]benzenesulfonic acid
BDBM50102303
Inchi KeyIANSGZBOXIJPDE-UHFFFAOYSA-N
Inchi IDInChI=1S/C14H16ClN3O12P2S/c1-7-13(19)9(5-29-31(20,21)22)10(6-30-32(23,24)25)14(16-7)18-17-12-4-8(33(26,27)28)2-3-11(12)15/h2-4,19H,5-6H2,1H3,(H2,20,21,22)(H2,23,24,25)(H,26,27,28)
PubChem CID135528154
ChEMBLN/A
IUPHARN/A
BindingDB50102303
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand has more than 5 hydrogen bond donor.
This ligand has more than 10 hydrogen bond acceptor.
This ligand is heavier than 500 daltons.

Experimental Data

ParameterValueReferenceDatabase source
IC50100000.0 nMPMID11462975BindingDB

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