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Name | Substance-P receptor |
---|---|
Species | Rattus norvegicus (Rat) |
Gene | Tacr1 |
Synonym | TAC1R Substance P receptor SPR NK1R NK1 receptor [ Show all ] |
Disease | N/A for non-human GPCRs |
Length | 407 |
Amino acid sequence | MDNVLPMDSDLFPNISTNTSESNQFVQPTWQIVLWAAAYTVIVVTSVVGNVVVIWIILAHKRMRTVTNYFLVNLAFAEACMAAFNTVVNFTYAVHNVWYYGLFYCKFHNFFPIAALFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVIFVIWVLALLLAFPQGYYSTTETMPSRVVCMIEWPEHPNRTYEKAYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHVFFLLPYINPDLYLKKFIQQVYLASMWLAMSSTMYNPIIYCCLNDRFRLGFKHAFRCCPFISAGDYEGLEMKSTRYLQTQSSVYKVSRLETTISTVVGAHEEEPEEGPKATPSSLDLTSNGSSRSNSKTMTESSSFYSNMLA |
UniProt | P14600 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL4027 |
IUPHAR | 360 |
DrugBank | N/A |
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GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
1105 | CHEMBL143156 | C27H30F6N2O2 | 528.539 | 9 / 0 | 5.6 | No |
1515 | CHEMBL556537 | C70H89F6N11O15 | 1438.53 | 22 / 14 | 5.8 | No |
1834 | CHEMBL2304114 | C97H126N18O19S | 1880.24 | 21 / 15 | 7.8 | No |
2433 | CHEMBL438422 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2434 | CHEMBL413304 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2435 | CHEMBL428315 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2436 | CHEMBL384274 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2437 | CHEMBL409406 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2438 | CHEMBL411977 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2439 | CHEMBL385507 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2440 | CHEMBL410402 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2441 | CHEMBL216901 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2442 | CHEMBL414911 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2443 | CHEMBL386194 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2444 | CHEMBL415827 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2445 | CHEMBL407601 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2446 | CHEMBL384088 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2447 | CHEMBL217596 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2448 | CHEMBL262941 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2449 | CHEMBL439278 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2450 | CHEMBL409993 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2451 | CHEMBL266426 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
441770 | CHEMBL411422 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2452 | CHEMBL385149 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2453 | CHEMBL439058 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2454 | CHEMBL276698 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2455 | CHEMBL406617 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2456 | CHEMBL441748 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
441771 | CHEMBL444093 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
441772 | CHEMBL411281 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2457 | CHEMBL439070 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2458 | CHEMBL411622 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2459 | CHEMBL408250 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2460 | CHEMBL383867 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2461 | CHEMBL415443 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2462 | CHEMBL263928 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
441773 | CHEMBL406623 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2463 | CHEMBL405236 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2464 | CHEMBL403499 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
441774 | CHEMBL425455 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
441775 | CHEMBL266075 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2465 | CHEMBL264585 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2466 | CHEMBL427648 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2467 | CHEMBL265852 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
441776 | CHEMBL264328 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2468 | CHEMBL415793 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2469 | CHEMBL413622 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2470 | CHEMBL438754 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2471 | CHEMBL264557 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2472 | CHEMBL414127 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2473 | CHEMBL408503 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2474 | CHEMBL386130 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2475 | CHEMBL424913 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2476 | CHEMBL217161 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2477 | CHEMBL407657 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
441777 | CHEMBL385148 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2478 | CHEMBL217432 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2479 | CHEMBL426159 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2480 | CHEMBL384394 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
441778 | CHEMBL384314 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2481 | CHEMBL438466 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2482 | CHEMBL269312 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2483 | CHEMBL405064 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2484 | CHEMBL407872 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2485 | CHEMBL409778 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2486 | CHEMBL414529 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2487 | Substance P | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2499 | CHEMBL264713 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2500 | CHEMBL410796 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2501 | CHEMBL267139 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2502 | CHEMBL412919 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
441779 | CHEMBL413406 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2503 | CHEMBL410018 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2504 | CHEMBL444112 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2505 | CHEMBL216569 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2506 | CHEMBL262964 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
441780 | CHEMBL405306 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2507 | CHEMBL404964 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2508 | CHEMBL262682 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2509 | CHEMBL410227 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2510 | CHEMBL406689 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2511 | CHEMBL276697 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2512 | CHEMBL267672 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2513 | CHEMBL415529 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2514 | CHEMBL265618 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2515 | CHEMBL415013 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2516 | CHEMBL405514 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2517 | CHEMBL383886 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2518 | CHEMBL217325 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2519 | CHEMBL407871 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2520 | CHEMBL415442 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2521 | CHEMBL402885 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2522 | CHEMBL436736 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2523 | CHEMBL438091 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2524 | CHEMBL405950 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2525 | CHEMBL262846 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2526 | CHEMBL262688 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2527 | CHEMBL415147 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2528 | CHEMBL430253 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
2529 | CHEMBL266517 | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
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