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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NameSubstance-K receptor
SpeciesRattus norvegicus (Rat)
GeneTacr2
SynonymSKR
NK2 receptor
Tachykinin receptor 2
Neurokinin B receptor
SP-E receptor
[ Show all ]
DiseaseN/A for non-human GPCRs
Length390
Amino acid sequenceMGTRAIVSDANILSGLESNATGVTAFSMPGWQLALWATAYLALVLVAVTGNATVIWIILAHERMRTVTNYFIINLALADLCMAAFNATFNFIYASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIAADRYMAIVHPFQPRLSAPSTKAIIAGIWLVALALASPQCFYSTITVDEGATKCVVAWPNDNGGKMLLLYHLVVFVLIYFLPLLVMFGAYSVIGLTLWKRAVPRHQAHGANLRHLQAKKKFVKAMVLVVLTFAICWLPYHLYFILGTFQEDIYYHKFIQQVYLALFWLAMSSTMYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTEEDRLELTHTPSLSRRVNRCHTKETLFMTGDMTHSEATNGQVGSPQDGEPAGPICKAQA
UniProtP16610
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL4554
IUPHAR361
DrugBankN/A

Known ligands

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Total entries: 328
Page:  / 4 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
8892D structureCHEMBL439281C39H47N7O6S741.9088 / 62.9No
24912D structureSubstance PC63H98N18O13S1347.6517 / 15-2.3No
39512D structureCHEMBL441206C75H109N19O131484.8216 / 150.5No
82842D structureCHEMBL565429C19H17N3287.3663 / 03.3Yes
111202D structureCHEMBL576844C20H17IN2412.2742 / 04.9Yes
116762D structureCHEMBL384541C63H96N14O12S1273.6115 / 121.2No
165292D structureCHEMBL335248C32H53N7O6S663.8798 / 71.4No
190242D structureGR-159897C23H27FN2O2S414.5395 / 13.4Yes
193912D structureCHEMBL566659C20H17BrN2365.2742 / 05.0Yes
204732D structureCHEMBL329888C46H58N8O11S931.07513 / 110.6No
247552D structureCHEMBL439377C38H45N7O4663.8236 / 53.3No
273672D structureCHEMBL367542C32H37Cl2N3O2566.5673 / 16.3No
297372D structureCHEMBL441454C45H66N12O7S919.1610 / 101.1No
307402D structureCHEMBL265115C49H76N12O9S1009.2811 / 100.9No
307442D structureCHEMBL412621C60H64N10O121117.2313 / 143.2No
5582492D structureCHEMBL266884C41H52N8O7S800.9768 / 62.8No
4429092D structureCHEMBL3349688C41H52N8O7S800.9768 / 62.8No
348492D structureCHEMBL262048C39H57N7O6S751.9888 / 63.0No
348532D structureCHEMBL407511C39H57N7O6S751.9888 / 63.0No
362172D structureL-732,138C22H18F6N2O3472.3879 / 24.7Yes
364012D structureCHEMBL225297C39H47N9O7S785.92110 / 71.2No
384912D structureCHEMBL436879C69H108N18O13S1429.817 / 14-0.5No
405392D structureMEN-10627C38H48N8O7S760.9118 / 82.0No
431052D structureCHEMBL157858C37H43N5O6653.786 / 43.4No
441562D structureCHEMBL410808C69H102N18O13S1423.7517 / 15-0.9No
495872D structureCHEMBL387199C56H64N10O11S1085.2513 / 132.6No
497372D structureCHEMBL2370054C49H67N9O11958.12711 / 83.6No
497952D structureCHEMBL3144343C41H44N6O6716.8396 / 33.8No
5588092D structureCHEMBL296267C41H44N6O6716.8396 / 33.8No
520272D structureGR 94800C49H61N9O8904.0828 / 74.4No
521672D structureCHEMBL224427C40H48N8O5720.8757 / 62.6No
521962D structureCHEMBL224003C39H45N7O5691.8336 / 52.8No
523092D structureCHEMBL71972C28H37Cl2N3O2518.5233 / 05.5No
556752D structureCHEMBL2370069C50H71N13O111030.212 / 93.5No
563052D structureCHEMBL122169C24H25F2N3O2425.485 / 14.1Yes
571982D structureCHEMBL264341C63H96N18O13S1345.6317 / 15-2.2No
572022D structureCHEMBL265573C63H96N18O13S1345.6317 / 15-2.2No
577172D structureCHEMBL173049C30H39N5O4533.6734 / 43.6No
4439692D structureCHEMBL3349531C36H47N7O6S705.8757 / 72.8No
5590712D structureCHEMBL268293C36H47N7O6S705.8757 / 72.8No
627482D structureCHEMBL1214027C72H90F6N12O11S21477.6920 / 118.5No
627542D structureCHEMBL1214026C72H90F6N12O11S21477.6920 / 118.5No
646212D structureCHEMBL565630C16H15ClN2270.762 / 03.7Yes
646782D structureCHEMBL412189C60H64N10O111101.2312 / 133.5No
649082D structureCHEMBL375214C47H57N9O12940.02412 / 12-0.7No
655622D structureCHEMBL122019C24H24F3N3O2443.476 / 14.2Yes
659782D structureCHEMBL422779C42H62N10O7S851.0819 / 81.9No
664482D structureCHEMBL173203C31H34Cl2N2O3553.5244 / 06.5No
680582D structureCHEMBL264353C69H100N18O13S1421.7317 / 15-1.2No
682362D structureCHEMBL327457C48H59N9O10S954.11312 / 111.1No
702442D structureCHEMBL224009C43H53N7O4731.9426 / 54.9No
5557592D structureCHEMBL299377C35H41Cl2N3O2606.6323 / 07.0No
728822D structureOsanetantC35H41Cl2N3O2606.6323 / 07.0No
734332D structureCHEMBL441181C50H60N10O11S1009.1513 / 130.3No
737762D structureCHEMBL125001C25H28FN3O2421.5164 / 14.4Yes
749632D structureCHEMBL576647C20H19NO2305.3773 / 11.8Yes
758682D structureCHEMBL338030C28H28FN3O2457.5494 / 15.2No
804022D structureCHEMBL438716C48H60N12O11981.08113 / 14-1.4No
804052D structureCHEMBL266526C48H60N12O11981.08113 / 14-1.4No
809432D structureCHEMBL225588C44H54N8O6790.9668 / 63.1No
825322D structureCHEMBL60459C23H27FN2O2382.4794 / 24.2Yes
832792D structureCHEMBL172938C24H28N4O3420.5133 / 43.2Yes
864502D structureCHEMBL68440C30H32Cl2N4O2551.5123 / 16.5No
920162D structureCHEMBL2370058C45H63N11O8886.0689 / 82.1No
5602082D structureCHEMBL427627C42H51N7O7S797.9728 / 63.6No
4454462D structureCHEMBL3349683C42H51N7O7S797.9728 / 63.6No
4454492D structureCHEMBL3349995C40H52N8O8S804.9649 / 71.8No
5602202D structureCHEMBL414195C40H52N8O8S804.9649 / 71.8No
942742D structureCHEMBL389432C38H45N7O4663.8236 / 63.1No
950522D structureCHEMBL2370050C42H67N11O9870.06610 / 81.2No
954392D structureCHEMBL586037C28H27NO2409.5293 / 06.4No
967372D structureCHEMBL293580C46H58N8O6819.027 / 63.9No
987612D structureCHEMBL2372521C71H102N18O13S1447.7717 / 15-1.0No
1012782D structureCHEMBL178959C44H69N11O9896.10410 / 71.5No
1032372D structureCHEMBL2372516C72H104N18O13S1461.817 / 14-0.4No
1034152D structureCHEMBL338825C24H27FN4O406.5053 / 23.4Yes
4458022D structureCHEMBL3349619C41H54N8O7S802.9928 / 72.9No
5605342D structureCHEMBL6241C41H54N8O7S802.9928 / 72.9No
4458032D structureCHEMBL3349990C41H54N8O7S802.9928 / 72.9No
5605352D structureCHEMBL2370528C41H54N8O7S802.9928 / 72.9No
1109492D structureCHEMBL170102C26H31N5O4477.5654 / 41.9Yes
1125262D structureNEUROKININ AC50H80N14O14S1133.3318 / 16-4.8No
5559102D structureSubstance KC50H80N14O14S1133.3318 / 16-4.8No
1125872D structureCHEMBL406487C57H67N13O111110.2413 / 150.8No
1125892D structureCHEMBL429340C57H67N13O111110.2413 / 150.8No
1125942D structureCHEMBL217365C57H67N13O111110.2413 / 150.8No
1148942D structureCHEMBL390167C41H48N8O6748.8857 / 72.2No
5609492D structureCHEMBL297376C44H48N6O8788.9028 / 43.2No
1179512D structureCHEMBL3144351C44H48N6O8788.9028 / 43.2No
1181352D structureCHEMBL387542C51H68N6O191069.1320 / 17-3.3No
1186202D structureSenktideC40H55N7O11S841.97812 / 81.1No
5610392D structureCHEMBL2370702C38H50N8O7S762.9278 / 82.2No
4464362D structure125989-12-0C38H50N8O7S762.9278 / 82.2No
1218332D structureCHEMBL2370056C51H65N9O9948.13510 / 73.8No
1232432D structureCHEMBL435619C23H28FN3O381.4954 / 33.2Yes
1252822D structureCHEMBL131872C42H68N10O11S921.12514 / 11-3.1No
1270052D structureCHEMBL223993C39H48N6O9744.84610 / 110.4No
1276352D structureCHEMBL566468C21H19N285.391 / 04.5Yes
1282942D structureCHEMBL340405C23H25FN4O2408.4775 / 12.9Yes
1291272D structureGR100679C34H44N6O5616.7635 / 53.4No

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