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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NameMelanocortin receptor 4
SpeciesRattus norvegicus (Rat)
GeneMc4r
SynonymMC4 receptor
MC4-R
DiseaseN/A for non-human GPCRs
Length332
Amino acid sequenceMNSTHHHGMYTSLHLWNRSSHGLHGNASESLGKGHSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVRRVGIIISCIWAACTVSGVLFIIYSDSSAVIICLITMFFTMLVLMASLYVHMFLMARLHIKRIAVLPGTGTIRQGANMKGAITLTILIGVFVVCWAPFFLHLLFYISCPQNPYCVCFMSHFNLYLILIMCNAVIDPLIYALRSQELRKTFKEIICFYPLGGICELPGRY
UniProtP70596
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL2700
IUPHAR285
DrugBankN/A

Known ligands

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Total entries: 20
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
123992D structureRY-764C34H51FN4O3582.8055 / 25.4No
186062D structureCHEMBL254757C31H40Cl3N3O2593.033 / 16.4No
201242D structureCHEMBL1209788C33H38ClF2N3O3598.1327 / 04.8No
333832D structureD0I8SJC90H127N25O26S2007.2131 / 27-10.1No
5583892D structureTAK-875C29H32O7S524.6287 / 14.7No
411392D structureCHEMBL393576C30H40Cl2FN5O2592.5816 / 24.4No
763352D structureAc-YR[CEHdFRWC]-NH2C60H79N19O13S21338.5318 / 18-2.0No
5383452D structureCHEMBL3287569C27H25ClN2O3460.9584 / 15.3No
1071432D structureCHEMBL439560C29H36ClF3N4O2565.0787 / 15.0No
5538092D structureSetmelanotideC49H68N18O9S21117.3214 / 15-2.5No
1177432D structureTHIQC33H41ClN6O2589.1815 / 25.9No
5625492D structureCHEMBL3930086C56H60CaN2O6S2961.30210 / 0N/ANo
1728252D structureMK-0489C34H44ClF2N3O2600.1925 / 15.8No
2060052D structureCHEMBL429854C31H40BrClFN3O2621.0324 / 15.9No
2060082D structureCHEMBL255286C31H40BrClFN3O2621.0324 / 15.9No
2639362D structureCHEMBL402769C32H41ClF3N3O2592.1446 / 16.0No
2703002D structureCHEMBL254589C31H40Cl2FN3O2576.5784 / 15.9No
3014722D structureCHEMBL497746C29H40ClFN4O2531.1135 / 15.0No
3412942D structureAc-dR[CEHdFRWC]-NH2C51H70N18O11S21175.3616 / 16-3.0No
4072482D structureCHEMBL368876C31H48FN5O3557.7556 / 33.9No

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