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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2436625
Molecular formula	C28H38FN5O2
IUPAC name	[1-[(2-aminopyridin-4-yl)methyl]-4-fluoropiperidin-4-yl]-[4-(7-methoxy-1,3,4,5-tetrahydro-2-benzazepin-2-yl)piperidin-1-yl]methanone
Molecular weight	495.643
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	3.0
Synonyms	BDBM50441506 SCHEMBL12549790
Inchi Key	BMWUIIPULBWCPO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H38FN5O2/c1-36-25-5-4-23-20-34(12-2-3-22(23)18-25)24-7-13-33(14-8-24)27(35)28(29)9-15-32(16-10-28)19-21-6-11-31-26(30)17-21/h4-6,11,17-18,24H,2-3,7-10,12-16,19-20H2,1H3,(H2,30,31)
PubChem CID	44622341
ChEMBL	CHEMBL2436625
IUPHAR	N/A
BindingDB	50441506
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
27839	Histamine H3 receptor	P58406	Hrh3	Mus musculus (Mouse)	445
27840	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445

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