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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL166737
Molecular formula	C25H23BrN4O2S
IUPAC name	1-(4-bromophenyl)-3-[[4-oxo-3-(3-propan-2-yloxyphenyl)quinazolin-2-yl]methyl]thiourea
Molecular weight	523.449
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	5.2
Synonyms	BDBM50291400 1-(4-Bromo-phenyl)-3-[3-(3-isopropoxy-phenyl)-4-oxo-3,4-dihydro-quinazolin-2-ylmethyl]-thiourea
Inchi Key	DFLAXXYUMGWHNF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H23BrN4O2S/c1-16(2)32-20-7-5-6-19(14-20)30-23(29-22-9-4-3-8-21(22)24(30)31)15-27-25(33)28-18-12-10-17(26)11-13-18/h3-14,16H,15H2,1-2H3,(H2,27,28,33)
PubChem CID	44379640
ChEMBL	CHEMBL166737
IUPHAR	N/A
BindingDB	50291400
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
58646	Cholecystokinin receptor type A	P30551	Cckar	Rattus norvegicus (Rat)	444
58645	Gastrin/cholecystokinin type B receptor	P56481	Cckbr	Mus musculus (Mouse)	453

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