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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL17334408
Molecular formula	C19H16F3N5O2
IUPAC name	2-[[4-(difluoromethoxy)-2-fluoroanilino]methyl]-5-pyridin-2-yl-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one
Molecular weight	403.365
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	3.1
Synonyms	US9676782, 151 BDBM197972 2-(((4-(difluoromethoxy)-2-fluorophenyl)amino)methyl)-5-(pyridin-2-yl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5h)-one
Inchi Key	FHQWOXATDDYFDQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H16F3N5O2/c20-14-10-13(29-19(21)22)4-5-15(14)24-11-12-9-16-18(28)26(7-8-27(16)25-12)17-3-1-2-6-23-17/h1-6,9-10,19,24H,7-8,11H2
PubChem CID	118575167
ChEMBL	N/A
IUPHAR	N/A
BindingDB	197972
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
559742	Metabotropic glutamate receptor 3	P31422	Grm3	Rattus norvegicus (Rat)	879
559741	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203

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