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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2431109
Molecular formula	C25H28N4O4
IUPAC name	[4-(2-cyclopropyl-6,7-dimethoxyquinazolin-4-yl)piperazin-1-yl]-(2-methoxyphenyl)methanone
Molecular weight	448.523
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	3.4
Synonyms	BDBM50440749 MLS-0469657.0001 SCHEMBL15818659
Inchi Key	FVWBKCQCHMXHOJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H28N4O4/c1-31-20-7-5-4-6-17(20)25(30)29-12-10-28(11-13-29)24-18-14-21(32-2)22(33-3)15-19(18)26-23(27-24)16-8-9-16/h4-7,14-16H,8-13H2,1-3H3
PubChem CID	56593279
ChEMBL	CHEMBL2431109
IUPHAR	N/A
BindingDB	50440749
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
88584	G-protein coupled receptor 35	Q9HC97	GPR35	Homo sapiens (Human)	309
88583	Neurotensin receptor type 1	P30989	NTSR1	Homo sapiens (Human)	418
88582	Neurotensin receptor type 2	O95665	NTSR2	Homo sapiens (Human)	410

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