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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL122420
Molecular formula	C32H40N4O3
IUPAC name	(E)-5-amino-N,5-dimethyl-N-[(2R)-1-[methyl-[(2R)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]amino]-3-naphthalen-1-yl-1-oxopropan-2-yl]hex-2-enamide
Molecular weight	528.697
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	4.2
Synonyms	SCHEMBL6318213 (E)-5-Amino-5-methyl-hex-2-enoic acid methyl-{(R)-1-[methyl-((R)-1-methylcarbamoyl-2-phenyl-ethyl)-carbamoyl]-2-naphthalen-1-yl-ethyl}-amide SCHEMBL6318847 BDBM50066824 N-(5-Amino-5-methyl-2-hexenoyl)-N-methyl-3-(1-naphthyl)-D-Ala-N-methyl-D-Phe-NHMe
Inchi Key	IFYWPHLAIJGALZ-YJBBJLKTSA-N
Inchi ID	InChI=1S/C32H40N4O3/c1-32(2,33)20-12-19-29(37)35(4)28(22-25-17-11-16-24-15-9-10-18-26(24)25)31(39)36(5)27(30(38)34-3)21-23-13-7-6-8-14-23/h6-19,27-28H,20-22,33H2,1-5H3,(H,34,38)/b19-12+/t27-,28-/m1/s1
PubChem CID	10744738
ChEMBL	CHEMBL122420
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
132354	Growth hormone secretagogue receptor type 1	Q92847	GHSR	Homo sapiens (Human)	366
132355	Growth hormone secretagogue receptor type 1	O08725	Ghsr	Rattus norvegicus (Rat)	364

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