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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	S(-)-Pindolol
Molecular formula	C14H20N2O2
IUPAC name	(2S)-1-(1H-indol-4-yloxy)-3-(propan-2-ylamino)propan-2-ol
Molecular weight	248.326
Hydrogen bond acceptor	3
Hydrogen bond donor	3
XlogP	1.8
Synonyms	NCGC00024973-03 SR-01000075488-1 ZINC56645 (S)-(-)-pindolol 328P110 BRD-K95598440-001-03-6 EU-0100349 Lopac0_000349 NCGC00261034-01 S-(-)-Pindolol SR-01000597475-1 (-)-pindolol ACM26328110 HMS2231C09 MLS001056774 PDSP2_000731 SMR000326991 UNII-BJ4HF6IU1D component JZQKKSLKJUAGIC-NSHDSACASA-N (2S)-1-(1H-indol-4-yloxy)-3-[(1-methylethyl)amino]propan-2-ol 2-propanol,1-(1h-indol-4-yloxy)-3-[(1-methylethyl)amino]-,(2s)- B6575 E34B58KY5W J-016382 NCGC00024973-01 NCGC00024973-04 S(-)-Pindolol, solid SR-01000075488-2 (S)-1-(1H-indol-4-yloxy)-3-[(1-methylethyl)amino]-2-propanol CCG-204444 EU-0101027 Lopac0_001027 P-152 SB17015 Tocris-1060 (2S)-1-(1H-indol-4-yloxy)-3-(isopropylamino)propan-2-ol 2-Propanal, 1-(1H-indol-4-yloxy)-3-((1-methylethyl)amino)-, (S)- AKOS024456358 CHEMBL117405 HMS3261E19 MolPort-003-959-160 NCGC00024973-02 Pindolol, (S)- SR-01000075488 UNII-E34B58KY5W (2S)-1-(1H-indol-4-yloxy)-3-[(propan-2-yl)amino]propan-2-ol 26328-11-0 BDBM50072755 espindolol KB-267891 NCGC00024973-05 S(?)-Pindolol SR-01000597475 (S)-pindolol AC1LELBQ CHEBI:48281 GTPL127 LP00349 PDSP1_000743 SCHEMBL5220 Tox21_500349 (2S)-1-(1H-indol-4-yloxy)-3-(propan-2-ylamino)propan-2-ol 2-Propanal,1-(1H-indol-4-yloxy)-3-((1-methylethyl)amino)-,(S)- API0005632 CTK8F2100 HMS3267E06 mt-102 [ Show all ]
Inchi Key	JZQKKSLKJUAGIC-NSHDSACASA-N
Inchi ID	InChI=1S/C14H20N2O2/c1-10(2)16-8-11(17)9-18-14-5-3-4-13-12(14)6-7-15-13/h3-7,10-11,15-17H,8-9H2,1-2H3/t11-/m0/s1
PubChem CID	688095
ChEMBL	CHEMBL117405
IUPHAR	127
BindingDB	50072755
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
163935	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
163936	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
554109	5-hydroxytryptamine receptor 1B	P28334	Htr1b	Mus musculus (Mouse)	386
163933	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
163932	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
163937	Beta-3 adrenergic receptor	P13945	ADRB3	Homo sapiens (Human)	408
483127	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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