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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL17418785
Molecular formula	C31H35FN2O5
IUPAC name	(3S)-3-cyclopropyl-3-[3-[[6-[(3,3-dimethylcyclobutyl)methoxy]-5-(2-fluoro-5-methoxyphenyl)pyrazin-2-yl]methoxy]phenyl]propanoic acid
Molecular weight	534.628
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	5.9
Synonyms	BDBM168199 US9688642, 42 (3S)-3-Cyclopropyl-3-(3-((6-((3,3-dimethylcyclobutyl)methoxy)-5-(2-fluoro-5-methoxyphenyl)pyrazin-2-yl)methoxy)phenyl)propanoic acid MAWNYSVJWWGRIH-VWLOTQADSA-N
Inchi Key	MAWNYSVJWWGRIH-VWLOTQADSA-N
Inchi ID	InChI=1S/C31H35FN2O5/c1-31(2)14-19(15-31)17-39-30-29(26-12-23(37-3)9-10-27(26)32)33-16-22(34-30)18-38-24-6-4-5-21(11-24)25(13-28(35)36)20-7-8-20/h4-6,9-12,16,19-20,25H,7-8,13-15,17-18H2,1-3H3,(H,35,36)/t25-/m0/s1
PubChem CID	118645565
ChEMBL	N/A
IUPHAR	N/A
BindingDB	168199
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
563620	Free fatty acid receptor 1	O14842	FFAR1	Homo sapiens (Human)	300
563621	Free fatty acid receptor 1	Q8K3T4	Ffar1	Rattus norvegicus (Rat)	300

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