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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL125498
Molecular formula	C30H38N4O3S
IUPAC name	(E)-5-amino-N,5-dimethyl-N-[(2R)-1-[methyl-[(2R)-1-(methylamino)-1-oxo-3-thiophen-2-ylpropan-2-yl]amino]-3-naphthalen-2-yl-1-oxopropan-2-yl]hex-2-enamide
Molecular weight	534.719
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	3.9
Synonyms	SCHEMBL6318260 BDBM50066827 N-(5-Amino-5-methyl-2-hexenoyl)-N-methyl-3-(2-naphthyl)-D-Ala-N-methyl-3-(2-thienyl)-D-Ala-NHMe SCHEMBL6318254 (E)-5-Amino-5-methyl-hex-2-enoic acid methyl-{(R)-1-[methyl-((R)-1-methylcarbamoyl-2-thiophen-2-yl-ethyl)-carbamoyl]-2-naphthalen-2-yl-ethyl}-amide
Inchi Key	NHBJGAPSMJFRON-YCGZWQSFSA-N
Inchi ID	InChI=1S/C30H38N4O3S/c1-30(2,31)16-8-13-27(35)33(4)26(19-21-14-15-22-10-6-7-11-23(22)18-21)29(37)34(5)25(28(36)32-3)20-24-12-9-17-38-24/h6-15,17-18,25-26H,16,19-20,31H2,1-5H3,(H,32,36)/b13-8+/t25-,26-/m1/s1
PubChem CID	10649999
ChEMBL	CHEMBL125498
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
223136	Growth hormone secretagogue receptor type 1	O08725	Ghsr	Rattus norvegicus (Rat)	364
223137	Growth hormone secretagogue receptor type 1	Q92847	GHSR	Homo sapiens (Human)	366

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