Zhang Lab

University of Michigan

Home Research COVID-19 Services Publications People Teaching Job Opening News Forum Lab Only

Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Colterol
Molecular formula	C12H19NO3
IUPAC name	4-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,2-diol
Molecular weight	225.288
Hydrogen bond acceptor	4
Hydrogen bond donor	4
XlogP	-0.4
Synonyms	1,2-Benzenediol, 4-[2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl]- ACM18866789 Colterolum N-tert-butyl-2-(3,4-dihydroxyphenyl)-2-hydroxyethylamine (+-)-N-tert-Butylarterenol 4-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,2-diol CHEBI:73085 dl-1-(3,4-Dihydroxyphenyl)-2-tert-butylaminoethanol t-Butylnorepinephrine 1,2-Benzenediol, 4-(2-((1,1-dimethylethyl)amino)-1-hydroxyethyl)- a-[(t-butylamino)methyl]-3,4-dihydroxy-benzyl alcohol KWD 2026 18866-78-9 BDBM50421728 Colterolum [INN-Latin] S 1541 (+-)-tert-Butyl noradrenaline 4363-02-4 dl-N-tert-Butylnorepinephrine Win 5563 1,2-Benzenediol, 4-(2-((1,1-dimethylethyl)amino)-1-hydroxyethyl)-,(+-)- AC1L18FI Colterol [INN] N-t-Butylarterenol (+-)-N-t-Butylnoradrenaline 4-(2-((1-Dimethylethyl)amino)-1-hydroxyethyl)-1,2-benzenediol Benzyl alcohol, alpha-((tert-butylamino)methyl)-3,4-dihydroxy-, (+-)- CTK1C8071 SCHEMBL249585 (+/-)-N-tert-butylarterenol CHEMBL1159715 FT-0716336 [ Show all ]
Inchi Key	PHSMOUBHYUFTDM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C12H19NO3/c1-12(2,3)13-7-11(16)8-4-5-9(14)10(15)6-8/h4-6,11,13-16H,7H2,1-3H3
PubChem CID	25104
ChEMBL	CHEMBL1159715
IUPHAR	N/A
BindingDB	50421728
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
260057	Beta-2 adrenergic receptor	Q28044	ADRB2	Bos taurus (Bovine)	418
260058	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
260059	Beta-2 adrenergic receptor	Q8K4Z4	Adrb2	Cavia porcellus (Guinea pig)	418

zhanglabzhanggroup.org | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218