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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL470292
Molecular formula	C25H28N2O4
IUPAC name	4-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]-2-propan-2-yloxybenzoic acid
Molecular weight	420.509
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	1.2
Synonyms	4-(2-{[(2R)-2-Hydroxy-2-(3-pyridinyl)ethyl]amino}ethyl)-3-isopropoxy-4-biphenylcarboxylic acid (R)-4''-(2-(2-hydroxy-2-(pyridin-3-yl)ethylamino)ethyl)-3-isopropoxybiphenyl-4-carboxylic acid BDBM50243064
Inchi Key	YNNCJPLSEBDJPD-QHCPKHFHSA-N
Inchi ID	InChI=1S/C25H28N2O4/c1-17(2)31-24-14-20(9-10-22(24)25(29)30)19-7-5-18(6-8-19)11-13-27-16-23(28)21-4-3-12-26-15-21/h3-10,12,14-15,17,23,27-28H,11,13,16H2,1-2H3,(H,29,30)/t23-/m0/s1
PubChem CID	24895783
ChEMBL	CHEMBL470292
IUPHAR	N/A
BindingDB	50243064
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
414626	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
414625	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
414623	Beta-3 adrenergic receptor	O02662	ADRB3	Canis lupus familiaris (Dog)	405
414624	Beta-3 adrenergic receptor	P13945	ADRB3	Homo sapiens (Human)	408

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