Hi there,
I submitted a job to I-TASSER (S114753) a couple months back. When I look at the template alignment there is a region within my protein that aligns according to my expectation, however, when I look at the actual model the two regions do not superimpose structurally.
My solution to fix this problem was to resubmit the job with the template and alignment specified, but since these regions are already aligned I'm not sure if this will work.
Any insight would be greatly appreciated. Thanks in advance