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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NameNociceptin receptor
SpeciesCavia porcellus (Guinea pig)
GeneOPRL1
SynonymKappa-type 3 opioid receptor
KOR-3
Orphanin FQ receptor
XOR
DiseaseN/A for non-human GPCRs
Length370
Amino acid sequenceMESLFPAPFWEVLYGSHLQGNLSLLSPNHSGLPPHLLLNASHSAFLPLGLKVTIVGLYLAVCIGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQATDILLGFWPFGNTLCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALALVVGVPVAIMGSAQVEDEEIECLVEIPDPQDYWGPVFAVSIFLFSFIIPVLIISVCYSLMIRRLHGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLVQGLGVQPGSETTVAILRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALHREMQVSDRVRSIAKDVALGCKTTETVPRPA
UniProtP47748
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL5492
IUPHARN/A
DrugBankN/A

Known ligands

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Total entries: 36
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
79852D structureCHEMBL378753C26H27N3O4445.5196 / 33.5Yes
156342D structureM3A6SC19H21NO7S407.4377 / 1-1.8Yes
303612D structuremorphineC17H19NO3285.3434 / 20.8Yes
694662D structureCHEMBL263588C79H131FN28O201812.0927 / 28-9.0No
864352D structureCHEMBL1418C17H19NO6S365.46 / 2-2.0Yes
914202D structureM3IBu6SC21H25NO7S435.4917 / 1-0.8Yes
935002D structureCHEMBL410145C82H141N35O211953.2531 / 33-13.3No
1062862D structureUFP-112C83H139FN32O211940.2329 / 34-10.7No
1211782D structureDAMGOC26H35N5O6513.5957 / 60.2No
1394152D structureM3B6SC24H23NO7S469.5088 / 1-0.1Yes
1520852D structureCHEMBL1417C18H21NO6S379.4277 / 1-1.5Yes
1804362D structureCHEMBL410653C82H141N35O211953.2531 / 33-13.4No
1832372D structureCHEMBL264846C79H129FN28O211826.0727 / 28-9.2No
1837372D structureBDBM50411363C83H140N32O211922.2428 / 31-11.9No
1981332D structureM3Pr6SC20H23NO7S421.4647 / 1-1.4Yes
2153082D structureCHEMBL414782C82H140FN35O211971.2432 / 33-13.3No
2215622D structureM3P6SC22H27NO7S449.5188 / 1-0.3Yes
2590982D structureCHEMBL1256748C22H32N2O2356.513 / 03.0Yes
4950772D structureU-69593C22H32N2O2356.513 / 03.0Yes
2691852D structureBDBM21842C79H129N27O221809.0727 / 28-11.0No
2782712D structureCHEMBL437744C84H142FN33O211969.2730 / 32-12.7No
2782772D structureCHEMBL2372052C84H142FN33O211969.2730 / 35-11.6No
2823932D structureMM3A6SC20H23NO7S421.4647 / 00.5Yes
2861922D structureDM6SC17H21NO6S367.4167 / 2-0.8Yes
2999332D structureMM3B6SC25H25NO7S483.5357 / 02.1Yes
3121532D structureCHEMBL411621C79H130N28O211808.0826 / 28-9.3No
3235772D structureCHEMBL262544C82H143N35O201939.2731 / 33-13.1No
3348652D structureCHEMBL1415C17H19NO6S365.46 / 2-2.1Yes
3354782D structureDC6SC18H23NO6S381.4437 / 1-0.5Yes
3472772D structureCHEMBL1783826C26H33Cl2N3O474.473 / 15.5No
3641692D structure122507-47-5C30H38ClN5O7S2680.23210 / 70.0No
3710512D structureCHEMBL413944C79H129FN28O211826.0727 / 28-9.2No
3935612D structureCHEMBL414767C79H132N28O201794.126 / 28-9.1No
4055492D structureDM3A6SC19H23NO7S409.4538 / 1-0.7Yes
4085042D structureDM3B6SC24H25NO7S471.5248 / 10.9Yes
4086722D structureMET-enkephalinC27H35N5O7S573.6659 / 7-2.1No

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