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Ligand

NameBDBM142208
Molecular formulaC24H25ClN4O4
IUPAC name5-[(5-chloropyridin-2-yl)methoxy]-2-[2-[4-[[(3R)-3-hydroxypyrrolidin-1-yl]methyl]-2-methylphenyl]-2-oxoethyl]pyridazin-3-one
Molecular weight468.938
Hydrogen bond acceptor7
Hydrogen bond donor1
XlogP1.9
SynonymsUS8933079, 7.9
Inchi KeyAHSZWDWETAJGMP-HXUWFJFHSA-N
Inchi IDInChI=1S/C24H25ClN4O4/c1-16-8-17(12-28-7-6-20(30)13-28)2-5-22(16)23(31)14-29-24(32)9-21(11-27-29)33-15-19-4-3-18(25)10-26-19/h2-5,8-11,20,30H,6-7,12-15H2,1H3/t20-/m1/s1
PubChem CID91759581
ChEMBLN/A
IUPHARN/A
BindingDB142208
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 1
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GLASS IDNameUniProtGeneSpeciesLength
557442Melanin-concentrating hormone receptor 1Q99705MCHR1Homo sapiens (Human)422

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