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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000699016
Molecular formula	C11H12N2O3S3
IUPAC name	2-[(5Z)-5-[(2E)-2-(3-methyl-1,3-thiazolidin-2-ylidene)ethylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]acetic acid
Molecular weight	316.408
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	2.0
Synonyms	AE-848/32742054 NCGC00247169-01 2-[(5Z)-5-[(2E)-2-(3-methyl-1,3-thiazolidin-2-ylidene)ethylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]acetic acid CHEMBL1586687 ZINC4013581 65152-09-2 KB-196420 2-[(5Z)-4-keto-5-[(2E)-2-(3-methylthiazolidin-2-ylidene)ethylidene]-2-thioxo-thiazolidin-3-yl]acetic acid BDBM46785 SCHEMBL6744220 {5-[2-(3-methyl-1,3-thiazolidin-2-ylidene)ethylidene]-4-oxo-2-thioxo-1,3-thiazolidin-3-yl}acetic acid 2-[(5Z)-5-[(2E)-2-(3-methyl-2-thiazolidinylidene)ethylidene]-4-oxo-2-sulfanylidene-3-thiazolidinyl]acetic acid cid_7072146 AC1OFAXK 2-[(5Z)-5-[(2E)-2-(3-methyl-1,3-thiazolidin-2-ylidene)ethylidene]-4-oxidanylidene-2-sulfanylidene-1,3-thiazolidin-3-yl]ethanoic acid SMR000230530 5-[(3-methylthiazolidin-2-ylidene)ethylidene]-4-oxo-2-thioxothiazolidin-3acetic acid HMS2603H22 [ Show all ]
Inchi Key	AMSAICQWZZDCEM-LHRDSYOJSA-N
Inchi ID	InChI=1S/C11H12N2O3S3/c1-12-4-5-18-8(12)3-2-7-10(16)13(6-9(14)15)11(17)19-7/h2-3H,4-6H2,1H3,(H,14,15)/b7-2-,8-3+
PubChem CID	7072146
ChEMBL	CHEMBL1586687
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
9188	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
9189	Thyrotropin-releasing hormone receptor	P34981	TRHR	Homo sapiens (Human)	398

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