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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL565707
Molecular formula	C25H31N3O4
IUPAC name	ethyl 5-[3-[4-(4-methoxyphenyl)piperazin-1-yl]propoxy]-1H-indole-2-carboxylate
Molecular weight	437.54
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.5
Synonyms	BDBM50300160 Ethyl 5-(3-(4-(4-methoxyphenyl)piperazin-1-yl)propoxy)-1H-indole-2-carboxylate
Inchi Key	AWAQTFZDZQIWSM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H31N3O4/c1-3-31-25(29)24-18-19-17-22(9-10-23(19)26-24)32-16-4-11-27-12-14-28(15-13-27)20-5-7-21(30-2)8-6-20/h5-10,17-18,26H,3-4,11-16H2,1-2H3
PubChem CID	45112565
ChEMBL	CHEMBL565707
IUPHAR	N/A
BindingDB	50300160
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
15847	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
15845	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
15846	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460

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