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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	spiropiperidine analogue, 70
Molecular formula	C29H39ClN4O
IUPAC name	3-[2-(butylamino)ethyl]-8-(7-chloro-1,2,3,4-tetrahydronaphthalen-1-yl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Molecular weight	495.108
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	5.6
Synonyms	BDBM26952 3-[2-(butylamino)ethyl]-8-(7-chloro-1,2,3,4-tetrahydronaphthalen-1-yl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one CHEMBL516187
Inchi Key	BEBLFDYTZHKBFQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H39ClN4O/c1-2-3-16-31-17-20-33-22-34(25-9-5-4-6-10-25)29(28(33)35)14-18-32(19-15-29)27-11-7-8-23-12-13-24(30)21-26(23)27/h4-6,9-10,12-13,21,27,31H,2-3,7-8,11,14-20,22H2,1H3
PubChem CID	25190627
ChEMBL	CHEMBL516187
IUPHAR	N/A
BindingDB	26952
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
21418	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
21421	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
21419	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400
21420	Nociceptin receptor	P41146	OPRL1	Homo sapiens (Human)	370

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