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Ligand

Namesildenafil
Molecular formulaC22H30N6O4S
IUPAC name5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-6H-pyrazolo[4,3-d]pyrimidin-7-one
Molecular weight474.58
Hydrogen bond acceptor8
Hydrogen bond donor1
XlogP1.5
Synonyms139755-83-2
VIAGRA
Sildenafil [INN:BAN]
UK-92480
UNII-3M7OB98Y7H
[ Show all ]
Inchi KeyBNRNXUUZRGQAQC-UHFFFAOYSA-N
Inchi IDInChI=1S/C22H30N6O4S/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29)
PubChem CID135398744
ChEMBLCHEMBL192
IUPHARN/A
BindingDB14390
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 3
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
28375Adenosine receptor A1P30542ADORA1Homo sapiens (Human)326
28374Adenosine receptor A2aP29274ADORA2AHomo sapiens (Human)412
28376Alpha-1B adrenergic receptorP15823Adra1bRattus norvegicus (Rat)515

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