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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL368556
Molecular formula	C12H12N2O5
IUPAC name	(2S)-2-amino-3-[4-(3-hydroxyphenyl)-3-oxo-1,2-oxazol-5-yl]propanoic acid
Molecular weight	264.237
Hydrogen bond acceptor	6
Hydrogen bond donor	4
XlogP	-2.3
Synonyms	(S)-2-Amino-3-[4-(3-hydroxyphenyl)-3-hydroxyisoxazole-5-yl]propionic acid BDBM50109652 2-Amino-3-[3-hydroxy-4-(3-hydroxy-phenyl)-isoxazol-5-yl]-propionic acid
Inchi Key	GQMGXQFOFZCRPO-QMMMGPOBSA-N
Inchi ID	InChI=1S/C12H12N2O5/c13-8(12(17)18)5-9-10(11(16)14-19-9)6-2-1-3-7(15)4-6/h1-4,8,15H,5,13H2,(H,14,16)(H,17,18)/t8-/m0/s1
PubChem CID	44385667
ChEMBL	CHEMBL368556
IUPHAR	N/A
BindingDB	50109652
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
102751	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
102750	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
560505	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
102752	Metabotropic glutamate receptor 4	P31423	Grm4	Rattus norvegicus (Rat)	912

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