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Ligand

NameCHEMBL1922015
Molecular formulaC22H24FN5O2
IUPAC name4-N-(3-fluoro-4-methoxyphenyl)-2-N-(4-methoxyphenyl)-6-pyrrolidin-1-ylpyrimidine-2,4-diamine
Molecular weight409.465
Hydrogen bond acceptor8
Hydrogen bond donor2
XlogP4.9
SynonymsSCHEMBL10144179
Inchi KeyIYBJEGSSKQTJDP-UHFFFAOYSA-N
Inchi IDInChI=1S/C22H24FN5O2/c1-29-17-8-5-15(6-9-17)25-22-26-20(14-21(27-22)28-11-3-4-12-28)24-16-7-10-19(30-2)18(23)13-16/h5-10,13-14H,3-4,11-12H2,1-2H3,(H2,24,25,26,27)
PubChem CID56643637
ChEMBLCHEMBL1922015
IUPHARN/A
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 2
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GLASS IDNameUniProtGeneSpeciesLength
144503Galanin receptor type 1P47211GALR1Homo sapiens (Human)349
144504Galanin receptor type 2O43603GALR2Homo sapiens (Human)387

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