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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL100340
Molecular formula	C24H29N5O3
IUPAC name	methyl N-[3-[4-[cyano-(2-methylpyridin-3-yl)methyl]piperazin-1-yl]-3-oxo-1-phenylpropyl]-N-methylcarbamate
Molecular weight	435.528
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	1.7
Synonyms	BDBM50046003 SCHEMBL9575074 (3-{4-[Cyano-(2-methyl-pyridin-3-yl)-methyl]-piperazin-1-yl}-3-oxo-1-phenyl-propyl)-methyl-carbamic acid methyl ester
Inchi Key	KCNFJCRMUHVBER-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H29N5O3/c1-18-20(10-7-11-26-18)22(17-25)28-12-14-29(15-13-28)23(30)16-21(27(2)24(31)32-3)19-8-5-4-6-9-19/h4-11,21-22H,12-16H2,1-3H3
PubChem CID	10071653
ChEMBL	CHEMBL100340
IUPHAR	N/A
BindingDB	50046003
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
165913	Platelet-activating factor receptor	P46002	Ptafr	Rattus norvegicus (Rat)	341
165914	Platelet-activating factor receptor	P21556	PTAFR	Cavia porcellus (Guinea pig)	342
165915	Platelet-activating factor receptor	Q62035	Ptafr	Mus musculus (Mouse)	341

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