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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	VU0152100
Molecular formula	C18H19N3O2S
IUPAC name	3-amino-N-[(4-methoxyphenyl)methyl]-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide
Molecular weight	341.429
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	3.9
Synonyms	D0K3HY ML 108 VU 0152100 3-amino-N-[(4-methoxyphenyl)methyl]-4,6-dimethylthieno[5,4-b]pyridine-2-carboxamide ASN 02869380 HY-13340 NCGC00370898-03 3-amino-4,6-dimethyl-N-p-anisyl-thieno[2,3-b]pyridine-2-carboxamide 409351-28-6 KS-0000004R SCHEMBL18293046 VU152100 3-Amino-N-[(4-methoxyphenyl)methyl]-4,6-dimethyl-thieno[2,3-b]pyridine-2-carboxamide AC1LHK0V CS-1727 DTXSID40357702 ML108 VU 152100 3-azanyl-N-[(4-methoxyphenyl)methyl]-4,6-dimethyl-thieno[2,3-b]pyridine-2-carboxamide BCP27623 KB-81469 Oprea1_056792 VU0152100, >=98% (HPLC) 3-Amino-N-(4-methoxybenzyl)-4,6-dimethylthieno[2,3-b]pyridine carboxamide 4155AH CHEMBL1978713 MCULE-8991282071 ST082340 ZINC420976 3-amino-N-[(4-methoxyphenyl)methyl]-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide AKOS024285191 CTK8G3776 GTPL3263 MolPort-000-013-635 VU-0152100 (3-amino-4,6-dimethylthiopheno[2,3-b]pyridin-2-yl)-N-[(4-methoxyphenyl)methyl] carboxamide BDBM48043 Kinome_1269 Oprea1_693584 VU0152100-1 3-amino-N-[(4-methoxyphenyl)methyl]-4,6-dimethyl-2-thieno[2,3-b]pyridinecarboxamide cid_864492 [ Show all ]
Inchi Key	MDNWGCQSCGNTKH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H19N3O2S/c1-10-8-11(2)21-18-14(10)15(19)16(24-18)17(22)20-9-12-4-6-13(23-3)7-5-12/h4-8H,9,19H2,1-3H3,(H,20,22)
PubChem CID	864492
ChEMBL	CHEMBL1978713
IUPHAR	3263
BindingDB	48043
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
202857	Muscarinic acetylcholine receptor M4	P08173	CHRM4	Homo sapiens (Human)	479
202858	Muscarinic acetylcholine receptor M4	P08485	Chrm4	Rattus norvegicus (Rat)	478

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