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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2112586
Molecular formula	C18H27NO4
IUPAC name	(1S,2S)-2-[3-(1-adamantyl)-1-amino-1-carboxypropyl]cyclopropane-1-carboxylic acid
Molecular weight	321.417
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	0.5
Synonyms	alpha-Amino-alpha-[2-(adamantan-1-yl)ethyl]-2beta-carboxycyclopropane-1alpha-acetic acid BDBM50408688
Inchi Key	MPKHVTSOJQASTK-SWBCKKISSA-N
Inchi ID	InChI=1S/C18H27NO4/c19-18(16(22)23,14-6-13(14)15(20)21)2-1-17-7-10-3-11(8-17)5-12(4-10)9-17/h10-14H,1-9,19H2,(H,20,21)(H,22,23)/t10?,11?,12?,13-,14-,17?,18?/m0/s1
PubChem CID	10567792
ChEMBL	CHEMBL2112586
IUPHAR	N/A
BindingDB	50408688
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
211177	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
211178	Metabotropic glutamate receptor 3	Q14832	GRM3	Homo sapiens (Human)	879

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