You can:
| Name | 5-hydroxytryptamine receptor 2A |
|---|---|
| Species | Bos taurus (Bovine) |
| Gene | HTR2A |
| Synonym | 5-HT-2 5-HT-2A Serotonin receptor 2A |
| Disease | N/A for non-human GPCRs |
| Length | 470 |
| Amino acid sequence | MDILCEENTSLSSTTNSLMQLHADTRLYSTDFNSGEGNTSNAFNWTVDSENRTNLSCEGCLSPPCFSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSTLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADENFVLIGSFVAFFIPLTIMVITYFLTIKSLQKEATLCVSDPGTRTKLASFSFLPQSSLSSEKLFQRSIHREPGSYGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNRDVIEALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGPKKNSKKDDKTTDNDCTMVALGKEHPEDAPADSSNTVNEKVSCV |
| UniProt | Q75Z89 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL3446 |
| IUPHAR | N/A |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 490 |  CHEMBL54125 | C22H21FN4 | 360.436 | 4 / 0 | 4.7 | Yes |
| 1865 |  CHEMBL53662 | C23H23FN4O | 390.462 | 5 / 0 | 4.7 | Yes |
| 4222 |  CHEMBL25984 | C15H23NO | 233.355 | 2 / 0 | 3.8 | Yes |
| 4971 |  CHEMBL50188 | C25H36N2O4 | 428.573 | 5 / 0 | 4.2 | Yes |
| 5542 |  CHEMBL50722 | C25H36N2O5 | 444.572 | 6 / 0 | 4.3 | Yes |
| 5919 |  CHEMBL50722 | C27H38N2O9 | 534.606 | 10 / 2 | N/A | No |
| 7262 |  CHEMBL54914 | C15H17N5 | 267.336 | 4 / 0 | 2.4 | Yes |
| 7854 |  CHEMBL63114 | C14H15N3S | 257.355 | 3 / 0 | 4.2 | Yes |
| 9614 |  CHEMBL418678 | C20H19FN4S | 366.458 | 5 / 0 | 4.7 | Yes |
| 10273 |  CHEMBL298649 | C22H22FN5 | 375.451 | 5 / 0 | 4.3 | Yes |
| 11732 |  propranolol | C16H21NO2 | 259.349 | 3 / 2 | 3.0 | Yes |
| 11812 |  CHEMBL54266 | C23H32N2O4S | 432.579 | 6 / 1 | 4.3 | Yes |
| 12302 |  CHEMBL52800 | C22H22FN5O | 391.45 | 6 / 0 | 4.3 | Yes |
| 13665 |  8-OH-Dpat | C16H25NO | 247.382 | 2 / 1 | 4.1 | Yes |
| 18210 |  CHEMBL49932 | C22H21N5O2 | 387.443 | 6 / 0 | 3.7 | Yes |
| 19995 |  CHEMBL53490 | C14H15N5 | 253.309 | 4 / 1 | 1.9 | Yes |
| 23243 |  DIHYDREXIDINE | C17H17NO2 | 267.328 | 3 / 3 | 2.5 | Yes |
| 23287 |  CHEMBL303986 | C19H23N5OS | 369.487 | 5 / 0 | 3.2 | Yes |
| 25956 |  CHEMBL62612 | C22H24N4S | 376.522 | 4 / 0 | 5.4 | No |
| 26647 |  CHEBI:48565 | C21H26N2O3 | 354.45 | 4 / 2 | 2.9 | Yes |
| 33238 |  CHEMBL410531 | C22H20ClFN4 | 394.878 | 4 / 0 | 5.3 | No |
| 41314 |  CHEMBL60318 | C20H22FN3OS | 371.474 | 5 / 0 | 3.9 | Yes |
| 42411 |  CHEMBL62911 | C21H23N4S+ | 363.503 | 3 / 0 | 4.6 | Yes |
| 44085 |  CHEMBL50456 | C21H19Cl2N5 | 412.318 | 4 / 0 | 5.1 | No |
| 45204 |  CHEMBL302225 | C14H16N4S | 272.37 | 4 / 0 | 3.1 | Yes |
| 53951 |  CHEMBL65736 | C17H20N4S | 312.435 | 4 / 0 | 3.9 | Yes |
| 54611 |  CHEMBL48925 | C25H34N2O4 | 426.557 | 5 / 1 | 4.6 | Yes |
| 56699 |  cisapride | C23H29ClFN3O4 | 465.95 | 7 / 2 | 3.4 | Yes |
| 57407 |  CHEMBL298534 | C24H31FN2O3 | 414.521 | 5 / 1 | 4.7 | Yes |
| 57913 |  CHEMBL53195 | C32H35N7 | 517.681 | 6 / 0 | 5.6 | No |
| 58999 |  CHEMBL66307 | C26H23ClN4S | 459.008 | 4 / 0 | 7.0 | No |
| 59260 |  CHEMBL64167 | C20H23N3OS | 353.484 | 4 / 0 | 3.8 | Yes |
| 59695 |  CHEMBL62366 | C20H20N4S | 348.468 | 4 / 0 | 4.8 | Yes |
| 62227 |  spiperone | C23H26FN3O2 | 395.478 | 5 / 1 | 3.0 | Yes |
| 62315 |  CHEMBL51888 | C22H30N2O4S | 418.552 | 6 / 1 | 3.9 | Yes |
| 62511 |  CHEMBL52438 | C19H25NO | 283.415 | 2 / 0 | 5.1 | No |
| 63076 |  CHEMBL11592 | C26H38N2O4 | 442.6 | 5 / 0 | 4.6 | Yes |
| 63269 |  CHEMBL63289 | C16H18N4O2S | 330.406 | 5 / 0 | 3.4 | Yes |
| 67037 |  CHEMBL65669 | C20H20N4S | 348.468 | 4 / 0 | 4.8 | Yes |
| 68944 |  CHEMBL301060 | C28H40N2O8 | 532.634 | 9 / 2 | N/A | No |
| 71630 |  CHEMBL261977 | C22H22N4S | 374.506 | 4 / 0 | 5.3 | No |
| 71961 |  CHEMBL62445 | C19H18N4S | 334.441 | 4 / 1 | 4.3 | Yes |
| 72742 |  CHEMBL59741 | C20H20F3N3OS | 407.455 | 7 / 1 | 4.5 | Yes |
| 78198 |  domperidone | C22H24ClN5O2 | 425.917 | 3 / 2 | 3.9 | Yes |
| 82337 |  CHEMBL52612 | C20H22N4 | 318.424 | 3 / 0 | 3.0 | Yes |
| 83890 |  Ketanserin | C22H22FN3O3 | 395.434 | 5 / 1 | 2.6 | Yes |
| 84686 |  CHEMBL63713 | C22H21F3N4S | 430.493 | 7 / 0 | 6.0 | No |
| 88081 |  CHEMBL296395 | C22H24N2O4 | 380.444 | 5 / 1 | 2.9 | Yes |
| 88268 |  CHEMBL50993 | C25H36N2O3 | 412.574 | 4 / 0 | 4.6 | Yes |
| 92984 |  CHEMBL300735 | C24H34N2O4S | 446.606 | 6 / 1 | 4.6 | Yes |
| 101635 |  5-Meo-dpac | C16H25NO2 | 263.381 | 3 / 0 | 3.8 | Yes |
| 103231 |  CHEMBL302431 | C20H18Cl2N4S | 417.352 | 4 / 0 | 5.9 | No |
| 112353 |  CHEMBL285010 | C14H19NO2 | 233.311 | 3 / 0 | 2.5 | Yes |
| 113162 |  CHEMBL62902 | C26H21F3N4S | 478.537 | 7 / 0 | 7.4 | No |
| 114701 |  CHEMBL63845 | C20H17F3N4S | 402.439 | 7 / 0 | 5.8 | No |
| 120665 |  CHEMBL54089 | C26H30N2O8 | 498.532 | 9 / 2 | N/A | N/A |
| 121671 |  CHEMBL294730 | C22H27N3O2S | 397.537 | 5 / 0 | 4.1 | Yes |
| 122918 |  CHEMBL52625 | C21H20FN5 | 361.424 | 5 / 0 | 4.0 | Yes |
| 124418 |  CHEMBL104985 | C14H18ClN3O | 279.768 | 4 / 0 | 3.4 | Yes |
| 135890 |  CHEMBL299097 | C21H21N5 | 343.434 | 4 / 0 | 4.0 | Yes |
| 136066 |  CHEMBL59823 | C24H31N3O3 | 409.53 | 5 / 0 | 3.6 | Yes |
| 140732 |  CHEMBL52396 | C25H30N2O4 | 422.525 | 5 / 0 | 4.3 | Yes |
| 142052 |  CHEMBL61819 | C23H29N3O2S | 411.564 | 5 / 0 | 4.4 | Yes |
| 142301 |  CHEMBL63790 | C21H20N4O2S | 392.477 | 6 / 0 | 4.4 | Yes |
| 143151 |  CHEMBL545198 | C23H26N2O4 | 394.471 | 5 / 0 | 3.6 | Yes |
| 146217 |  GR 103691 | C30H35N3O3 | 485.628 | 5 / 1 | 4.8 | Yes |
| 148974 |  CHEMBL63905 | C19H17FN4S | 352.431 | 5 / 0 | 5.0 | Yes |
| 152202 |  CYPROHEPTADINE | C21H21N | 287.406 | 1 / 0 | 4.7 | Yes |
| 152917 |  CHEMBL51985 | C27H41N2O4+ | 457.635 | 4 / 0 | 4.6 | Yes |
| 153118 |  CHEMBL545198 | C23H27ClN2O4 | 430.929 | 5 / 1 | N/A | N/A |
| 160443 |  CHEMBL300692 | C23H23FN4 | 374.463 | 4 / 0 | 5.1 | No |
| 166259 |  CHEMBL416662 | C23H21ClN4O2 | 420.897 | 5 / 0 | 5.1 | No |
| 169280 |  CHEMBL54266 | C25H34N2O8S | 522.613 | 10 / 3 | N/A | No |
| 173359 |  CHEMBL51985 | C27H41IN2O4 | 584.539 | 5 / 0 | N/A | No |
| 182093 |  CHEMBL52485 | C24H36N2O4 | 416.562 | 5 / 0 | 3.7 | Yes |
| 183079 |  CHEMBL293219 | C26H21F3N4S | 478.537 | 7 / 0 | 7.5 | No |
| 189345 |  CHEMBL50841 | C24H34N2O4 | 414.546 | 5 / 0 | 3.9 | Yes |
| 191595 |  haloperidol | C21H23ClFNO2 | 375.868 | 4 / 1 | 3.2 | Yes |
| 194908 |  fluphenazine enanthate | C29H38F3N3O2S | 549.697 | 9 / 0 | 7.4 | No |
| 196477 |  CHEMBL284912 | C21H34N2O3 | 362.514 | 5 / 0 | 3.3 | Yes |
| 198701 |  CGS 12066B | C17H17F3N4 | 334.346 | 6 / 0 | 4.0 | Yes |
| 203489 |  CUMI-101 | C19H27N5O3 | 373.457 | 6 / 0 | 1.8 | Yes |
| 208397 |  CHEMBL416747 | C22H36N2O2 | 360.542 | 4 / 0 | 4.5 | Yes |
| 211956 |  CHEMBL292293 | C13H13N3OS | 259.327 | 4 / 0 | 3.0 | Yes |
| 212747 |  CHEMBL64727 | C20H18Cl2N4S | 417.352 | 4 / 0 | 5.9 | No |
| 213415 |  CHEMBL62274 | C16H18N4S | 298.408 | 4 / 0 | 3.8 | Yes |
| 228334 |  CHEMBL415933 | C23H28N6O | 404.518 | 5 / 0 | 3.7 | Yes |
| 231548 |  CHEMBL51888 | C24H32N2O8S | 508.586 | 10 / 3 | N/A | No |
| 240592 |  Phentolamine mesylate | C18H23N3O4S | 377.459 | 6 / 3 | N/A | N/A |
| 244518 |  A-131701 | C24H24N4O3S | 448.541 | 6 / 1 | 3.2 | Yes |
| 250991 |  CHEMBL292725 | C21H20N4O2S | 392.477 | 6 / 0 | 4.4 | Yes |
| 252652 |  CHEMBL48925 | C27H36N2O8 | 516.591 | 9 / 3 | N/A | No |
| 253042 |  CHEMBL65710 | C20H20N4S | 348.468 | 4 / 0 | 4.6 | Yes |
| 253193 |  CHEMBL51225 | C20H19N5 | 329.407 | 4 / 0 | 4.2 | Yes |
| 253504 |  CHEMBL65974 | C14H16N4S | 272.37 | 4 / 0 | 3.1 | Yes |
| 254622 |  CHEMBL53416 | C22H22N4 | 342.446 | 3 / 0 | 4.6 | Yes |
| 255091 |  CHEMBL298534 | C26H33FN2O7 | 504.555 | 9 / 3 | N/A | No |
| 257681 |  CHEMBL50530 | C24H34N2O4 | 414.546 | 5 / 0 | 3.6 | Yes |
| 259604 |  CHEMBL299561 | C26H38N2O7 | 490.597 | 8 / 2 | N/A | N/A |
| 266580 |  CHEMBL293879 | C17H20N4O2S | 344.433 | 6 / 0 | 3.4 | Yes |
zhanglab
zhanggroup.org | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218