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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NameMuscarinic acetylcholine receptor M4
SpeciesGallus gallus (Chicken)
GeneCHRM4
SynonymN/A
DiseaseN/A for non-human GPCRs
Length490
Amino acid sequenceMHNLSAQPWQAKMANLTYDNVTLSNRSEVAIQPPTNYKTVELVFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFSLACADLIIGVFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWILSFILWAPAILFWQFIVGKRTVHERECYIQFLSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVRRHKPESRKERKGKSLSFFKAPPVKQNNNNSPKRAVEVKEEVRNGKVDDQPSAQTEATGQQEEKETSNESSTVSMTQTTKDKPTTEILPAGQGQSPAHPRVNPTSKWSKIKIVTKQTGTESVTAIEIVPAKAGASDHNSLSNSRPANVARKFASIARSQVRKKRQMAAREKKVTRTIFAILLAFILTWTPYNVMVLINTFCETCVPETVWSIGYWLCYVNSTINPACYALCNATFKKTFKHLLMCQYRNIGTAR
UniProtP17200
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLN/A
IUPHARN/A
DrugBankN/A

Known ligands

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Total entries: 27
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
30942D structurePROPYLBENZILYLCHOLINE MUSTARDC21H26ClNO3375.8934 / 14.2Yes
228692D structuretropicamideC17H20N2O2284.3593 / 11.5Yes
420862D structureDABDMAC22H25NO319.4482 / 04.2Yes
510562D structuredicyclomineC19H35NO2309.4943 / 05.5No
606582D structureAprofeneC21H27NO2325.4523 / 03.8Yes
821322D structureHimbacineC22H35NO2345.5273 / 05.0Yes
972432D structureCogentinolC21H25NO307.4372 / 04.5Yes
1255652D structuretrihexyphenidylC20H31NO301.4742 / 14.5Yes
1271022D structure4-Diphenylacetoxy-1,1-dimethylpiperidiniumC21H26NO2+324.4442 / 04.0Yes
1777402D structurepiperidolateC21H25NO2323.4363 / 04.4Yes
2395582D structureipratropiumC20H30NO3+332.4643 / 12.6Yes
2855232D structureeucatropineC17H25NO3291.3914 / 12.8Yes
2862182D structurehexahydrosiladifenidolC20H33NOSi331.5752 / 1N/AN/A
2881852D structureorphenadrineC18H23NO269.3882 / 03.8Yes
2894332D structureBotiacrineC20H24N2OS340.4853 / 04.7Yes
2986052D structureL-HyoscyamineC17H23NO3289.3754 / 11.8Yes
2997372D structurepirenzepineC19H21N5O2351.415 / 10.1Yes
3020042D structureMethoctramineC36H62N4O2582.9186 / 46.8No
3169302D structurecyclopentolateC17H25NO3291.3914 / 12.7Yes
3226342D structurescopolamineC17H21NO4303.3585 / 10.9Yes
3634552D structureTelenzepineC19H22N4O2S370.4715 / 11.7Yes
3689552D structureSecoverineC22H35NO2345.5273 / 05.1No
3852422D structureprocyclidineC19H29NO287.4472 / 14.1Yes
3928252D structureesoxybutyninC22H31NO3357.4944 / 14.2Yes
4096752D structureBTM-1086C21H25N3OS367.5114 / 12.7Yes
4185342D structurebiperidenC21H29NO311.4692 / 14.3Yes
4372762D structureHOMATROPINEC16H21NO3275.3484 / 11.9Yes

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