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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NameProstaglandin E2 receptor EP3 subtype
SpeciesRattus norvegicus (Rat)
GenePtger3
SynonymEP3 receptor
PGE receptor EP3 subtype
PGE2 receptor EP3 subtype
prostaglandin E receptor 3
prostanoid EP3 receptor
DiseaseN/A for non-human GPCRs
Length365
Amino acid sequenceMAGVWAPEHSVEAHSNQSSAADGCGSVSVAFPITMMVTGFVGNALAMLLVVRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTSPVVILVYLSQRRWEQLDPSGRLCTFFGLTMTVFGLSSLLVASAMAVERALAIRAPHWYASHMKTRATPVLLGVWLSVLAFALLPVLGVGRYSVQWPGTWCFISTGPAGNETDSAREPGSVAFASAFACLGLLALVVTFACNLATIKALVSRCRAKAAASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNQMSVEQCKTQMGKEKECNSFLIAVRLASLNQILDPWVYLLLRKILLRKFCQIRDHTNYASSSTSLPCPGSSVLMWSDQLER
UniProtP34980
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL5674
IUPHAR342
DrugBankN/A

Known ligands

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Total entries: 26
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
5533682D structureprostaglandin D2C20H32O5352.4715 / 32.6Yes
5556342D structureindomethacinC19H16ClNO4357.794 / 14.3Yes
5535822D structureDoprostonC20H34O4338.4884 / 24.2Yes
5536802D structure17-phenyl-trinor-PGE2C23H30O5386.4885 / 32.8Yes
940482D structureCHEMBL563480C19H16Cl2N4O2S435.3236 / 14.7Yes
5537472D structurealprostadilC20H34O5354.4875 / 33.2Yes
1105502D structureCHEMBL2035510C21H17FN2O4380.3755 / 23.7Yes
5538392D structureILOPROSTC22H32O4360.4944 / 32.8Yes
1267312D structureCHEMBL1770317C21H18N2O4362.3854 / 23.6Yes
5541852D structureGR 63799C34H37NO8587.6698 / 33.9No
1866952D structureCHEMBL2035509C19H20N2O4340.3794 / 23.0Yes
5542402D structureONO-8713C25H24F3NO6S523.52310 / 15.7No
5542632D structureU 46619C21H34O4350.4994 / 23.9Yes
2174522D structureCHEMBL1271476C21H20ClN3O2381.862 / 24.1Yes
5544432D structureDpt-prostaglandin E1C22H30O5374.4775 / 23.5Yes
5545402D structurebutaprost acidC23H38O5394.5525 / 33.9Yes
5546002D structureenprostilC23H28O6400.4716 / 21.3Yes
5546242D structuredinoprostC20H34O5354.4875 / 42.7Yes
2801452D structureMK-2894C25H22F3NO3S473.517 / 25.9No
5567042D structurerofecoxibC17H14O4S314.3554 / 02.3Yes
3354822D structureCHEMBL2035508C20H19N3O4365.3894 / 22.4Yes
3395992D structureCID 70681702C18H12N2O4320.3044 / 22.4Yes
5549862D structureSulprostoneC23H31NO7S465.5617 / 31.5Yes
5552482D structureProstaglandin E2C20H32O5352.4715 / 32.8Yes
4188342D structureBDBM50384442C18H12N2O4320.3044 / 32.4Yes
5554752D structureSC46275C25H36O5416.5585 / 22.8Yes

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