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Ligand

NameCHEMBL3122225
Molecular formulaC19H21N5O2
IUPAC name[1-methyl-6-(pyridin-2-ylmethoxy)pyrazolo[3,4-b]pyridin-3-yl]-[(2R)-2-methylpyrrolidin-1-yl]methanone
Molecular weight351.41
Hydrogen bond acceptor5
Hydrogen bond donor0
XlogP2.3
SynonymsBDBM50448150
Inchi KeyCFGXSLFUPKEOSD-CYBMUJFWSA-N
Inchi IDInChI=1S/C19H21N5O2/c1-13-6-5-11-24(13)19(25)17-15-8-9-16(21-18(15)23(2)22-17)26-12-14-7-3-4-10-20-14/h3-4,7-10,13H,5-6,11-12H2,1-2H3/t13-/m1/s1
PubChem CID76321786
ChEMBLCHEMBL3122225
IUPHARN/A
BindingDB50448150
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 3
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
40638Metabotropic glutamate receptor 1Q13255GRM1Homo sapiens (Human)1194
40636Metabotropic glutamate receptor 5P31424Grm5Rattus norvegicus (Rat)1203
40637Metabotropic glutamate receptor 5P41594GRM5Homo sapiens (Human)1212

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