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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL194727
Molecular formula	C22H28FN3O2
IUPAC name	4-fluoro-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]benzamide
Molecular weight	385.483
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.6
Synonyms	4-fluoro-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)benzamide BDBM50172865 4-Fluoro-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-benzamide
Inchi Key	HGRPPZKIXIZLRX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H28FN3O2/c1-28-21-7-3-2-6-20(21)26-16-14-25(15-17-26)13-5-4-12-24-22(27)18-8-10-19(23)11-9-18/h2-3,6-11H,4-5,12-17H2,1H3,(H,24,27)
PubChem CID	44403210
ChEMBL	CHEMBL194727
IUPHAR	N/A
BindingDB	50172865
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
114440	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
114441	D(1A) dopamine receptor	P50130	DRD1	Sus scrofa (Pig)	446
114437	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
114438	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
114439	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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