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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	AC1M4HAF
Molecular formula	C19H19N3O4S
IUPAC name	1-[4-(3,4-dimethoxyphenyl)-1,3-thiazol-2-yl]-3-(3-methoxyphenyl)urea
Molecular weight	385.438
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	3.4
Synonyms	MLS001171445 1-[4-(3,4-dimethoxyphenyl)-1,3-thiazol-2-yl]-3-(3-methoxyphenyl)urea Oprea1_332663 CHEMBL1448905 SMR000592281 AKOS025066517 [ Show all ]
Inchi Key	HGSUMHXWPLRTOW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H19N3O4S/c1-24-14-6-4-5-13(10-14)20-18(23)22-19-21-15(11-27-19)12-7-8-16(25-2)17(9-12)26-3/h4-11H,1-3H3,(H2,20,21,22,23)
PubChem CID	2307751
ChEMBL	CHEMBL1448905
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
114502	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
114503	Lutropin-choriogonadotropic hormone receptor	P22888	LHCGR	Homo sapiens (Human)	699
114504	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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