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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	4-Phosphonoisovaline
Molecular formula	C5H12NO5P
IUPAC name	2-amino-2-methyl-4-phosphonobutanoic acid
Molecular weight	197.127
Hydrogen bond acceptor	6
Hydrogen bond donor	4
XlogP	-4.6
Synonyms	BDBM85016 STL526534 2-amino-2-methyl-4-phosphonobutyric acid L000381 AC1MYFVS NSC_1795545 CAS_1795545 MCULE-2760958330 AKOS030493351 SCHEMBL179782 2-amino-2-methyl-4-phosphonobutanoic acid CTK8H1062 MolPort-000-838-222 [ Show all ]
Inchi Key	HONKEGXLWUDTCF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C5H12NO5P/c1-5(6,4(7)8)2-3-12(9,10)11/h2-3,6H2,1H3,(H,7,8)(H2,9,10,11)
PubChem CID	3831196
ChEMBL	N/A
IUPHAR	N/A
BindingDB	85016
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
120160	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
120159	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
538965	Metabotropic glutamate receptor 4	P31423	Grm4	Rattus norvegicus (Rat)	912

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